A case report of comprehensive treatment for primary intraspinal carcinosarcoma

BackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwe...

Full description

Saved in:
Bibliographic Details
Main Authors: Chang Yan, Chao-Jun Zhang, Jun-bao Wei, Hui-wen Liang, Song Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1479193/full
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:BackgroundCarcinosarcoma is a rare and highly aggressive biphasic malignant tumor. To date, no cases of primary intraspinal carcinosarcoma have been reported.Case presentationThis study reports a case of a 36-year-old female with primary intra dural extramedullary carcinosarcoma. The patient underwent surgery at initial diagnosis, followed by two courses of radiotherapy due to residual tumor, as part of a comprehensive antitumor treatment. Despite good tumor control, she ultimately died of respiratory failure.DiscussionThis is the first reported case of primary intra dural extramedullary carcinosarcoma, detailing its imaging characteristics, pathological morphology, and treatment process. The tumor was responsive to radiotherapy. The rapid progression of intraspinal carcinosarcoma suggests it may be underdiagnosed or underreported, highlighting the need for more cases for clinical evaluation and treatment strategies.
ISSN:2234-943X