Mitochondrial metabolic regulation of macrophage polarization in osteomyelitis and other orthopedic disorders: mechanisms and therapeutic opportunities
Osteomyelitis is a complex infectious bone disease involving pathogen invasion, host immune responses, and dysregulation of the local microenvironment. As a critical component of the innate immune system, macrophages play a pivotal role in inflammatory responses and tissue repair. Their polarization...
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| Main Authors: | Jinglin Li, Lin Zhang, Jiaze Peng, Chuntao Zhao, Wenguang Li, Yang Yu, Xianpeng Huang, Fuyin Yang, Xuan Deng, Xuxu Yang, Tao Zhang, Jiachen Peng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2025.1604320/full |
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