FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI

Abstract Ankylosing Spondylitis (AS), commonly known as Bechterew’s disease, is a complex, potentially disabling disease that develops slowly over time and progresses to radiographic sacroiliitis. The etiology of this disease is poorly understood, making it difficult to diagnose. Therefore, treatmen...

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Main Author: Sıtkı Kocaoğlu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-08593-z
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author Sıtkı Kocaoğlu
author_facet Sıtkı Kocaoğlu
author_sort Sıtkı Kocaoğlu
collection DOAJ
description Abstract Ankylosing Spondylitis (AS), commonly known as Bechterew’s disease, is a complex, potentially disabling disease that develops slowly over time and progresses to radiographic sacroiliitis. The etiology of this disease is poorly understood, making it difficult to diagnose. Therefore, treatment is also delayed. This study aims to diagnose AS with an automated system that classifies axial magnetic resonance imaging (MRI) sequences of AS patients. Recently, the application of deep learning neural networks (DLNNs) for MRI classification has become widespread. The implementation of this process on computer-independent end devices is advantageous due to its high computational power and low latency requirements. In this research, an MRI dataset containing images from 527 individuals was used. A deep learning architecture on a Field Programmable Gate Array (FPGA) card was implemented and analyzed. The results show that the classification performed on FPGA in AS diagnosis yields successful results close to the classification performed on CPU.
format Article
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institution Kabale University
issn 2045-2322
language English
publishDate 2025-07-01
publisher Nature Portfolio
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series Scientific Reports
spelling doaj-art-89abe01c6f844064bf71550bc6abf7fe2025-08-20T03:45:23ZengNature PortfolioScientific Reports2045-23222025-07-011511810.1038/s41598-025-08593-zFPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRISıtkı Kocaoğlu0Biomedical Engineering Department, Ankara Yıldırım Beyazıt UniversityAbstract Ankylosing Spondylitis (AS), commonly known as Bechterew’s disease, is a complex, potentially disabling disease that develops slowly over time and progresses to radiographic sacroiliitis. The etiology of this disease is poorly understood, making it difficult to diagnose. Therefore, treatment is also delayed. This study aims to diagnose AS with an automated system that classifies axial magnetic resonance imaging (MRI) sequences of AS patients. Recently, the application of deep learning neural networks (DLNNs) for MRI classification has become widespread. The implementation of this process on computer-independent end devices is advantageous due to its high computational power and low latency requirements. In this research, an MRI dataset containing images from 527 individuals was used. A deep learning architecture on a Field Programmable Gate Array (FPGA) card was implemented and analyzed. The results show that the classification performed on FPGA in AS diagnosis yields successful results close to the classification performed on CPU.https://doi.org/10.1038/s41598-025-08593-zAnkylosing spondilitisFPGADLNNDiagnosis
spellingShingle Sıtkı Kocaoğlu
FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI
Scientific Reports
Ankylosing spondilitis
FPGA
DLNN
Diagnosis
title FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI
title_full FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI
title_fullStr FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI
title_full_unstemmed FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI
title_short FPGA implementation of deep learning architecture for ankylosing spondylitis detection from MRI
title_sort fpga implementation of deep learning architecture for ankylosing spondylitis detection from mri
topic Ankylosing spondilitis
FPGA
DLNN
Diagnosis
url https://doi.org/10.1038/s41598-025-08593-z
work_keys_str_mv AT sıtkıkocaoglu fpgaimplementationofdeeplearningarchitectureforankylosingspondylitisdetectionfrommri