Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method

Hemodynamic monitoring can reflect cardiac function and blood perfusion and is an indispensable monitoring method in clinical practice. Invasive hemodynamic monitoring methods represented by the thermodilution method are limited in their clinical application scope because they require vascular cannu...

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Main Authors: Fuhao KANG, Qi YIN, Yanan LIU, Lin HUANG, Yan HANG, Jilun YE, Xu ZHANG
Format: Article
Language:zho
Published: Editorial Office of Chinese Journal of Medical Instrumentation 2025-01-01
Series:Zhongguo yiliao qixie zazhi
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Online Access:https://zgylqxzz.xml-journal.net/article/doi/10.12455/j.issn.1671-7104.240364
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author Fuhao KANG
Qi YIN
Yanan LIU
Lin HUANG
Yan HANG
Jilun YE
Xu ZHANG
author_facet Fuhao KANG
Qi YIN
Yanan LIU
Lin HUANG
Yan HANG
Jilun YE
Xu ZHANG
author_sort Fuhao KANG
collection DOAJ
description Hemodynamic monitoring can reflect cardiac function and blood perfusion and is an indispensable monitoring method in clinical practice. Invasive hemodynamic monitoring methods represented by the thermodilution method are limited in their clinical application scope because they require vascular cannulation. Non-invasive hemodynamic monitoring has attracted extensive attention from medical companies and clinicians at home and abroad in recent years due to its advantages such as safety, non-invasiveness, continuous monitoring, simple operation, and low cost. This paper designs a non-invasive hemodynamic monitoring system based on the impedance cardiography, including hardware, algorithm, software design, and performance parameter evaluation. Among them, the hardware part mainly includes a differential high-frequency constant current source stimulation circuit, impedance cardiogram signal acquisition, and ECG signal acquisition circuit. Signal processing includes wave filtering, impedance cardiogram signal calibration, and ECG signal and impedance cardiogram signal feature point recognition. According to the collected impedance cardiogram and ECG signals, hemodynamic parameters such as heart rate (HR), stroke volume (SV), cardiac output (CO), stroke index (SI), cardiac index (CI), and cardiac contractility index (ICON) are calculated based on the Nyboer thoracic cylinder model. After testing, the key technical indicators of the system hardware are better than that of the relevant medical device standards. The system was used to collect impedance cardiogram and ECG signal data from 40 volunteers. The calculated HR, SV, and CO, three important hemodynamic indicators, were compared with the ICONCore non-invasive cardiac output monitor of OSYPKA Medical in Germany. Their Pearson correlation coefficients were 0.992 (P<0.001), 0.948 (P<0.001), and 0.933 (P<0.001), respectively, verifying that the designed system has high accuracy and reliability.
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language zho
publishDate 2025-01-01
publisher Editorial Office of Chinese Journal of Medical Instrumentation
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spelling doaj-art-89ab6d2bfbad42019abce0845a1682482025-08-20T03:18:06ZzhoEditorial Office of Chinese Journal of Medical InstrumentationZhongguo yiliao qixie zazhi1671-71042025-01-01491808810.12455/j.issn.1671-7104.2403642024-0364Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram MethodFuhao KANG0Qi YIN1Yanan LIU2Lin HUANG3Yan HANG4Jilun YE5Xu ZHANG6School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, 518037Hemodynamic monitoring can reflect cardiac function and blood perfusion and is an indispensable monitoring method in clinical practice. Invasive hemodynamic monitoring methods represented by the thermodilution method are limited in their clinical application scope because they require vascular cannulation. Non-invasive hemodynamic monitoring has attracted extensive attention from medical companies and clinicians at home and abroad in recent years due to its advantages such as safety, non-invasiveness, continuous monitoring, simple operation, and low cost. This paper designs a non-invasive hemodynamic monitoring system based on the impedance cardiography, including hardware, algorithm, software design, and performance parameter evaluation. Among them, the hardware part mainly includes a differential high-frequency constant current source stimulation circuit, impedance cardiogram signal acquisition, and ECG signal acquisition circuit. Signal processing includes wave filtering, impedance cardiogram signal calibration, and ECG signal and impedance cardiogram signal feature point recognition. According to the collected impedance cardiogram and ECG signals, hemodynamic parameters such as heart rate (HR), stroke volume (SV), cardiac output (CO), stroke index (SI), cardiac index (CI), and cardiac contractility index (ICON) are calculated based on the Nyboer thoracic cylinder model. After testing, the key technical indicators of the system hardware are better than that of the relevant medical device standards. The system was used to collect impedance cardiogram and ECG signal data from 40 volunteers. The calculated HR, SV, and CO, three important hemodynamic indicators, were compared with the ICONCore non-invasive cardiac output monitor of OSYPKA Medical in Germany. Their Pearson correlation coefficients were 0.992 (P<0.001), 0.948 (P<0.001), and 0.933 (P<0.001), respectively, verifying that the designed system has high accuracy and reliability.https://zgylqxzz.xml-journal.net/article/doi/10.12455/j.issn.1671-7104.240364impedance cardiogramnon-invasivecardiac outputnyboer thoracic cavity cylindrical model
spellingShingle Fuhao KANG
Qi YIN
Yanan LIU
Lin HUANG
Yan HANG
Jilun YE
Xu ZHANG
Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method
Zhongguo yiliao qixie zazhi
impedance cardiogram
non-invasive
cardiac output
nyboer thoracic cavity cylindrical model
title Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method
title_full Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method
title_fullStr Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method
title_full_unstemmed Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method
title_short Design and Implementation of Non-Invasive Hemodynamic Monitoring System Based on Impedance Cardiogram Method
title_sort design and implementation of non invasive hemodynamic monitoring system based on impedance cardiogram method
topic impedance cardiogram
non-invasive
cardiac output
nyboer thoracic cavity cylindrical model
url https://zgylqxzz.xml-journal.net/article/doi/10.12455/j.issn.1671-7104.240364
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AT linhuang designandimplementationofnoninvasivehemodynamicmonitoringsystembasedonimpedancecardiogrammethod
AT yanhang designandimplementationofnoninvasivehemodynamicmonitoringsystembasedonimpedancecardiogrammethod
AT jilunye designandimplementationofnoninvasivehemodynamicmonitoringsystembasedonimpedancecardiogrammethod
AT xuzhang designandimplementationofnoninvasivehemodynamicmonitoringsystembasedonimpedancecardiogrammethod