Enhanced efficacy of sequential administration of fosfomycin and linezolid against methicillin-resistant Staphylococcus aureus

Enhanced efficacy of sequential administration of fosfomycin and linezolid against methicillin-resistant Staphylococcus aureus

The aim of this study was to assess the superiority of sequential administration of fosfomycin and linezolid in combination on the efficacy of methicillin-resistant Staphylococcus aureus (MRSA). The antimicrobial activity was assessed using static and dynamic bactericidal assays, along with pharmaco...

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Bibliographic Details
Main Authors: Zaixing Chen, Qin Ai, Shuai Zheng, Ziyan Chen, Sailan Wang, Na Zhang, Huiping Liu, Yanyan Liu, Jiabin Li, Xiaohui Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
linezolid
fosfomycin
sequential administration
MRSA
PK/PD
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1511707/full
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