Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes

Ketogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach for weight reduction, particularly in young adults. However, a serious but rare complication of the ketogenic diet is ketoacidosis associated with low carbohydrate intake, which should be cautiously mon...

Full description

Saved in:
Bibliographic Details
Main Authors: Suranut Charoensri, Jin Sothornwit, Akeatit Trirattanapikul, Chatlert Pongchaiyakul
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2021/6620832
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832547716017684480
author Suranut Charoensri
Jin Sothornwit
Akeatit Trirattanapikul
Chatlert Pongchaiyakul
author_facet Suranut Charoensri
Jin Sothornwit
Akeatit Trirattanapikul
Chatlert Pongchaiyakul
author_sort Suranut Charoensri
collection DOAJ
description Ketogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach for weight reduction, particularly in young adults. However, a serious but rare complication of the ketogenic diet is ketoacidosis associated with low carbohydrate intake, which should be cautiously monitored in people with a predisposition to the condition. We report a 22-year-old Thai woman with an unremarkable past medical history who presented with an acute onset of dyspnea of 2 days’ duration. Diabetic ketoacidosis was diagnosed by elevated capillary blood glucose, significant metabolic acidosis, and a high serum beta-hydroxybutyrate level. Low C-peptide level and positive islet autoantibodies confirmed the new diagnosis of type 1 diabetes in this patient. After her conditions were stabilized, the patient revealed that she began a ketogenic diet for weight reduction 4 days before her illness. Other precipitating factors were not identified. This highlights that ketogenic diet may increase diabetic ketoacidosis risk at the presentation of previously unrecognized type 1 diabetes.
format Article
id doaj-art-89a02ce3b89646bd90f5c54a9170781f
institution Kabale University
issn 2090-6501
2090-651X
language English
publishDate 2021-01-01
publisher Wiley
record_format Article
series Case Reports in Endocrinology
spelling doaj-art-89a02ce3b89646bd90f5c54a9170781f2025-02-03T06:43:35ZengWileyCase Reports in Endocrinology2090-65012090-651X2021-01-01202110.1155/2021/66208326620832Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 DiabetesSuranut Charoensri0Jin Sothornwit1Akeatit Trirattanapikul2Chatlert Pongchaiyakul3Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDivision of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandKetogenic diet, a very low-carbohydrate diet and high-fat diet, has emerged as a popular approach for weight reduction, particularly in young adults. However, a serious but rare complication of the ketogenic diet is ketoacidosis associated with low carbohydrate intake, which should be cautiously monitored in people with a predisposition to the condition. We report a 22-year-old Thai woman with an unremarkable past medical history who presented with an acute onset of dyspnea of 2 days’ duration. Diabetic ketoacidosis was diagnosed by elevated capillary blood glucose, significant metabolic acidosis, and a high serum beta-hydroxybutyrate level. Low C-peptide level and positive islet autoantibodies confirmed the new diagnosis of type 1 diabetes in this patient. After her conditions were stabilized, the patient revealed that she began a ketogenic diet for weight reduction 4 days before her illness. Other precipitating factors were not identified. This highlights that ketogenic diet may increase diabetic ketoacidosis risk at the presentation of previously unrecognized type 1 diabetes.http://dx.doi.org/10.1155/2021/6620832
spellingShingle Suranut Charoensri
Jin Sothornwit
Akeatit Trirattanapikul
Chatlert Pongchaiyakul
Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes
Case Reports in Endocrinology
title Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes
title_full Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes
title_fullStr Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes
title_full_unstemmed Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes
title_short Ketogenic Diet-Induced Diabetic Ketoacidosis in a Young Adult with Unrecognized Type 1 Diabetes
title_sort ketogenic diet induced diabetic ketoacidosis in a young adult with unrecognized type 1 diabetes
url http://dx.doi.org/10.1155/2021/6620832
work_keys_str_mv AT suranutcharoensri ketogenicdietinduceddiabeticketoacidosisinayoungadultwithunrecognizedtype1diabetes
AT jinsothornwit ketogenicdietinduceddiabeticketoacidosisinayoungadultwithunrecognizedtype1diabetes
AT akeatittrirattanapikul ketogenicdietinduceddiabeticketoacidosisinayoungadultwithunrecognizedtype1diabetes
AT chatlertpongchaiyakul ketogenicdietinduceddiabeticketoacidosisinayoungadultwithunrecognizedtype1diabetes