An immunoregulation PLGA/Chitosan aligned nanofibers with polydopamine coupling basic fibroblast growth factor and ROS scavenging for peripheral nerve regeneration

An immunoregulation PLGA/Chitosan aligned nanofibers with polydopamine coupling basic fibroblast growth factor and ROS scavenging for peripheral nerve regeneration

The repair and functional recovery of long-segment peripheral nerve injuries are crucial in clinical settings. Nerve conduits are seen as promising alternatives to autologous nerve grafts, but their effectiveness is limited by the controlled delivery of bioactive factors and meeting various function...

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Bibliographic Details
Main Authors: Xiaokun Chen, Jihai Xu, Feng Qin, Ziyuan Yang, Xueyuan Li, Miao Yu, Ming Li, Yanhua Wang, Wang Xin
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Materials Today Bio
Subjects:
Composite nerve conduits
Electrospun nanofibers
Polydopamine
Immune modulation
Peripheral nerve regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425001012
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