Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report

Aisyah Shofiatun Nisa, Hadi Susiarno, Gatot Nyarumenteng Adipurnawan Winarno, Putri Nadhira Adinda Adriansyah Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, IndonesiaCorrespondence: Aisyah Shofiatun Nisa, Departmen...

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Main Authors: Nisa AS, Susiarno H, Winarno GNA, Adriansyah PNA
Format: Article
Language:English
Published: Dove Medical Press 2025-08-01
Series:International Medical Case Reports Journal
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Online Access:https://www.dovepress.com/non-immune-hydrops-fetalis-in-a-pregnant-woman-with-chronic-alcohol-us-peer-reviewed-fulltext-article-IMCRJ
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author Nisa AS
Susiarno H
Winarno GNA
Adriansyah PNA
author_facet Nisa AS
Susiarno H
Winarno GNA
Adriansyah PNA
author_sort Nisa AS
collection DOAJ
description Aisyah Shofiatun Nisa, Hadi Susiarno, Gatot Nyarumenteng Adipurnawan Winarno, Putri Nadhira Adinda Adriansyah Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, IndonesiaCorrespondence: Aisyah Shofiatun Nisa, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin Hospital, Jl. Pasteur 38, Bandung, West Java, 40161, Indonesia, Email aisyah23009@mail.unpad.ac.idIntroduction: Hydrops fetalis is a condition characterized by excessive fluid accumulation within the fetal extravascular compartments and body cavities. It is classified into two categories: immune hydrops fetalis (IHF) and non-immune hydrops fetalis (NIHF). The primary cause of NIHF is fetal cardiovascular abnormalities, often stemming from congenital heart disease. One of the significant contributors to congenital heart defects is prenatal alcohol exposure (PAE).Case Illustration: A woman in her early 30s presented to the emergency department with the chief complaint of not feeling fetal movements for one day prior to admission. This was her fourth pregnancy, with no history of miscarriage or abortion. The patient reported a history of regular smoking (two packs per day) and frequent alcohol consumption. Her vital signs were unremarkable upon admission. The baby was delivered weighing 1755 grams and measuring 44 cm, with grade 2 maceration and no signs of life. Physical findings, including fluid accumulation in the chest and body, led to a pediatric diagnosis of hydrops fetalis.Conclusion: The risk factor for hydrops fetalis in this case is likely associated with prenatal alcohol exposure, which may have disrupted fetal teratogenesis. Comprehensive prenatal examinations are essential for monitoring fetal health, identifying complications and congenital abnormalities, and assessing risk factors.Keywords: hydrops fetalis, non-immune hydrops fetalis, prenatal alcohol exposure, congenital heart disease
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publishDate 2025-08-01
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series International Medical Case Reports Journal
spelling doaj-art-8978adaba75645bf929d2ac33b339c732025-08-20T03:44:01ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2025-08-01Volume 18Issue 1969975105465Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case ReportNisa AS0Susiarno H1Winarno GNA2Adriansyah PNA3Obstetrics and GynecologyObstetrics and GynecologyObstetrics and GynecologyObstetrics and GynecologyAisyah Shofiatun Nisa, Hadi Susiarno, Gatot Nyarumenteng Adipurnawan Winarno, Putri Nadhira Adinda Adriansyah Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin General Hospital, Bandung, IndonesiaCorrespondence: Aisyah Shofiatun Nisa, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran – Dr. Hasan Sadikin Hospital, Jl. Pasteur 38, Bandung, West Java, 40161, Indonesia, Email aisyah23009@mail.unpad.ac.idIntroduction: Hydrops fetalis is a condition characterized by excessive fluid accumulation within the fetal extravascular compartments and body cavities. It is classified into two categories: immune hydrops fetalis (IHF) and non-immune hydrops fetalis (NIHF). The primary cause of NIHF is fetal cardiovascular abnormalities, often stemming from congenital heart disease. One of the significant contributors to congenital heart defects is prenatal alcohol exposure (PAE).Case Illustration: A woman in her early 30s presented to the emergency department with the chief complaint of not feeling fetal movements for one day prior to admission. This was her fourth pregnancy, with no history of miscarriage or abortion. The patient reported a history of regular smoking (two packs per day) and frequent alcohol consumption. Her vital signs were unremarkable upon admission. The baby was delivered weighing 1755 grams and measuring 44 cm, with grade 2 maceration and no signs of life. Physical findings, including fluid accumulation in the chest and body, led to a pediatric diagnosis of hydrops fetalis.Conclusion: The risk factor for hydrops fetalis in this case is likely associated with prenatal alcohol exposure, which may have disrupted fetal teratogenesis. Comprehensive prenatal examinations are essential for monitoring fetal health, identifying complications and congenital abnormalities, and assessing risk factors.Keywords: hydrops fetalis, non-immune hydrops fetalis, prenatal alcohol exposure, congenital heart diseasehttps://www.dovepress.com/non-immune-hydrops-fetalis-in-a-pregnant-woman-with-chronic-alcohol-us-peer-reviewed-fulltext-article-IMCRJHydrops FetalisNon-Immune Hydrops FetalisPrenatal Alcohol ExposureCongenital Heart Disease
spellingShingle Nisa AS
Susiarno H
Winarno GNA
Adriansyah PNA
Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report
International Medical Case Reports Journal
Hydrops Fetalis
Non-Immune Hydrops Fetalis
Prenatal Alcohol Exposure
Congenital Heart Disease
title Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report
title_full Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report
title_fullStr Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report
title_full_unstemmed Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report
title_short Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report
title_sort non immune hydrops fetalis in a pregnant woman with chronic alcohol use a case report
topic Hydrops Fetalis
Non-Immune Hydrops Fetalis
Prenatal Alcohol Exposure
Congenital Heart Disease
url https://www.dovepress.com/non-immune-hydrops-fetalis-in-a-pregnant-woman-with-chronic-alcohol-us-peer-reviewed-fulltext-article-IMCRJ
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AT adriansyahpna nonimmunehydropsfetalisinapregnantwomanwithchronicalcoholuseacasereport