Activity-dependent synthesis of Emerin gates neuronal plasticity by regulating proteostasis
Summary: Neurons dynamically regulate their proteome in response to sensory input, a key process underlying experience-dependent plasticity. We characterized the visual experience-dependent nascent proteome in mice within a brief, defined time window after stimulation using an optimized metabolic la...
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| Main Authors: | Yi Xie, Ruoxi Wang, Daniel B. McClatchy, Yuanhui Ma, Jolene Diedrich, Manuel Sanchez-Alavez, Michael Petrascheck, John R. Yates, III, Hollis T. Cline |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-04-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725002104 |
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