Hypoalbuminemia and cisplatin-induced acute kidney injury

Hypoalbuminemia and cisplatin-induced acute kidney injury

BackgroundCisplatin binds to serum albumin in the body at a rate of 90%, and high levels of free cisplatin are a significant cause of its nephrotoxicity. Therefore, hypoalbuminemia theoretically poses a significant risk factor for cisplatin-induced acute kidney injury (CIA) and can be easily correct...

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Bibliographic Details
Main Authors: Wen-Jun Yin, Yu-Jie Huang, Qing Zhu, Xiao-Qing Lin, Hui-Ling Piao, Qian-Qian Yu, Chang-Hong Lai, Guang-Liang Zhou, Ling-Yun Zhou, Kun Liu, Xiao-Cong Zuo, Shan-Ru Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
cisplatin
acute kidney injury
hypoalbuminemia
meta-analysis
retrospective study
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1510477/full
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