A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives

Oxygen heterocycles represent a significant category of organic molecules that are abundant in nature and important in scientific research due to their use in diverse applications across various fields. Coumarins, in particular, comprise a wide range of compounds known for their extensive biological...

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Main Authors: Asmaa Kebaili, Fatima Belhadj, Zahira Kibou, Julio A. Seijas, M. Pilar Vazquez Tato, Noureddine Choukchou-Braham
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
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Online Access:https://www.mdpi.com/2673-4583/16/1/41
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author Asmaa Kebaili
Fatima Belhadj
Zahira Kibou
Julio A. Seijas
M. Pilar Vazquez Tato
Noureddine Choukchou-Braham
author_facet Asmaa Kebaili
Fatima Belhadj
Zahira Kibou
Julio A. Seijas
M. Pilar Vazquez Tato
Noureddine Choukchou-Braham
author_sort Asmaa Kebaili
collection DOAJ
description Oxygen heterocycles represent a significant category of organic molecules that are abundant in nature and important in scientific research due to their use in diverse applications across various fields. Coumarins, in particular, comprise a wide range of compounds known for their extensive biological activities, making them invaluable in medicine, pharmacology, cosmetics, and the food industry. The biological effects and potential applications of coumarins are closely tied to their specific chemical structures. As a result, researchers frequently engage in the synthesis of coumarin derivatives to explore their varied uses. In this context, we focused on the synthesis of 3-cyano-coumarin and its derivatives. This study introduces a simple synthesis method that enables the efficient and accessible production of these structures under mild, environmentally friendly conditions, yielding excellent results.
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institution Kabale University
issn 2673-4583
language English
publishDate 2024-11-01
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series Chemistry Proceedings
spelling doaj-art-895f81fbabfa42ecbb4a3fa20aaa982f2025-08-20T03:26:21ZengMDPI AGChemistry Proceedings2673-45832024-11-011614110.3390/ecsoc-28-20113A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine DerivativesAsmaa Kebaili0Fatima Belhadj1Zahira Kibou2Julio A. Seijas3M. Pilar Vazquez Tato4Noureddine Choukchou-Braham5Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119, Tlemcen 13000, AlgeriaLaboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119, Tlemcen 13000, AlgeriaLaboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119, Tlemcen 13000, AlgeriaDepartamento de Quimica Orgànica, Facultad de Ciencias, Universidad de Santiago de Compostela, A da, Alfonso X EL Sabio s/n, 27002 Lugo, SpainDepartamento de Quimica Orgànica, Facultad de Ciencias, Universidad de Santiago de Compostela, A da, Alfonso X EL Sabio s/n, 27002 Lugo, SpainLaboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119, Tlemcen 13000, AlgeriaOxygen heterocycles represent a significant category of organic molecules that are abundant in nature and important in scientific research due to their use in diverse applications across various fields. Coumarins, in particular, comprise a wide range of compounds known for their extensive biological activities, making them invaluable in medicine, pharmacology, cosmetics, and the food industry. The biological effects and potential applications of coumarins are closely tied to their specific chemical structures. As a result, researchers frequently engage in the synthesis of coumarin derivatives to explore their varied uses. In this context, we focused on the synthesis of 3-cyano-coumarin and its derivatives. This study introduces a simple synthesis method that enables the efficient and accessible production of these structures under mild, environmentally friendly conditions, yielding excellent results.https://www.mdpi.com/2673-4583/16/1/41organic synthesisoxygen heterocycles3-cyano-coumarine derivatives
spellingShingle Asmaa Kebaili
Fatima Belhadj
Zahira Kibou
Julio A. Seijas
M. Pilar Vazquez Tato
Noureddine Choukchou-Braham
A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives
Chemistry Proceedings
organic synthesis
oxygen heterocycles
3-cyano-coumarine derivatives
title A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives
title_full A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives
title_fullStr A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives
title_full_unstemmed A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives
title_short A Straightforward and Efficient Approach to the Synthesis of 3-Cyano-Coumarine Derivatives
title_sort straightforward and efficient approach to the synthesis of 3 cyano coumarine derivatives
topic organic synthesis
oxygen heterocycles
3-cyano-coumarine derivatives
url https://www.mdpi.com/2673-4583/16/1/41
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