Recovery from AMPA Receptor Potentiation by Ampakines

Recovery from AMPA Receptor Potentiation by Ampakines

Background: Ampakines are a family of molecules that enhance the functioning of AMPA-glutamate receptors (AMPAR). High-impact ampakines completely offset receptor desensitization and enhance agonist binding affinity, while low-impact ampakines only modestly affect receptor desensitization and do not...

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Bibliographic Details
Main Authors: Daniel P. Radin, Rok Cerne, Jodi L. Smith, Jeffrey M. Witkin, Arnold Lippa
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Future Pharmacology
Subjects:
ampakine
AMPA receptor
low-impact ampakine
high-impact ampakine
CX516
CX614
Online Access:https://www.mdpi.com/2673-9879/5/2/27
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