Adaptive hydrogel loaded with pre-coordinated stem cells for enhanced osteoarthritis therapy

Adaptive hydrogel loaded with pre-coordinated stem cells for enhanced osteoarthritis therapy

Osteoarthritis (OA) is a prevalent chronic joint disease with no currently available cure. Despite the promise of mesenchymal stromal cells (MSCs) in promoting OA management, direct intra-articular administration of MSCs faces several critical challenges, including rapid cell clearance from the join...

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Bibliographic Details
Main Authors: Chenyuan Gao, Wenli Dai, Dingge Liu, Xinyu Wang, Tianyun Zhang, Bingzheng Yu, Yingjie Yu, Hua Tian, Xiaoping Yang, Qing Cai
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Bioactive Materials
Subjects:
Osteoarthritis
Cell therapy
Hypoxia
Chondrogenic
Injectable hydrogel
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25002129
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