The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle

The article highlights the specifics of the effect of various doses of a complex of B vitamins (B1, B2, B5, B6, B10, B12) on the activity of critical enzymes of the body's antioxidant defense system (superoxide dismutase, catalase, glutathione peroxidase) and the content of peroxide oxidation p...

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Main Authors: P. I. Golovach, B. V. Gutyj, I. A. Kolomiiets, D. D. Ostapiv, R. S. Oseredchuk, O. M. Sloboda
Format: Article
Language:English
Published: Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv 2023-12-01
Series:Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
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Online Access:https://nvlvet.com.ua/index.php/journal/article/view/4946
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author P. I. Golovach
B. V. Gutyj
I. A. Kolomiiets
D. D. Ostapiv
R. S. Oseredchuk
O. M. Sloboda
author_facet P. I. Golovach
B. V. Gutyj
I. A. Kolomiiets
D. D. Ostapiv
R. S. Oseredchuk
O. M. Sloboda
author_sort P. I. Golovach
collection DOAJ
description The article highlights the specifics of the effect of various doses of a complex of B vitamins (B1, B2, B5, B6, B10, B12) on the activity of critical enzymes of the body's antioxidant defense system (superoxide dismutase, catalase, glutathione peroxidase) and the content of peroxide oxidation products (diene conjugates and Malan dialdehyde) in the blood of cattle at the final stage of fattening. The research was conducted during the winter-spring stall on 12-month-old Ukrainian black-spotted dairy cows. According to the principle of analogs, five groups of experimental animals (control and four experimental) were formed, each with six heads. The experiment lasted six months. The rations for the research groups of Bugai cattle are prepared by the recommended norms, taking into account the chemical composition of the fodder of the given area, the age of the animals, live weight, and the planned average daily growth. The silage type of fattening was used for feeding the Bugai cattle. The basis of our dosage of various vitamins of group B for fattening steers of experimental groups is the appropriate percentage of the recommended doses of individual vitamins of group B for fattening pigs (10 % – D1, 20 % – D2, 40 % – D3, 60 % – D4 group). The conducted studies established that the addition of a complex of B vitamins (B1, B2, B5, B6, B10, B12) balanced in terms of nutrients and minerals and fat-soluble vitamins A, D, E to the diet of fattening bulls in appropriate doses causes an increase in activity of critical enzymes of the antioxidant defense system in the blood of fattening bulls (the activity of superoxide dismutase increases the most (by 8.9–28.4 %)) and a decrease in the content of both primary (diene conjugates) and secondary (malanic dialdehyde) products of lipid peroxidation in the blood of fattening bulls, which depends on the dose of B vitamins added to the diet (B1, B2, B5, B6, B10, B12). The most significant change in terms of morphological composition in animals third (B1 – 0.040; B2 – 0.06; B5 – 1.2; B6 – 0.25; B10 – 0.0030; B12 – 0.0006 mg/kg body weight) and fourth (B1 – 0.070; B2 – 0.10; B5 – 2.0; B6 – 0.40; B10 – 0.0050; B12 – 0.0010 mg/kg body weight) research groups, and smallest – in bull Ist (B1 – 0.015; B2 – 0.03; B5 – 0.5; B6 – 0.10; B10 – 0.0012; B12 – 0.0002 mg/kg body weight) and research group, which is associated with dose introduced to the diet of calves during the final fattening phase of B vitamins (B1, B2, B5, B6, B10, B12).
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series Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
spelling doaj-art-893271f1fab34f29ba01ea48e74577c82025-08-20T03:29:32ZengStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies LvivНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки2518-75542518-13272023-12-0125112222610.32718/nvlvet112034946The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattleP. I. Golovach0B. V. Gutyj1I. A. Kolomiiets2D. D. Ostapiv3R. S. Oseredchuk4O. M. Sloboda5Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineInstitute of Animal Biology NAAS, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, UkraineThe article highlights the specifics of the effect of various doses of a complex of B vitamins (B1, B2, B5, B6, B10, B12) on the activity of critical enzymes of the body's antioxidant defense system (superoxide dismutase, catalase, glutathione peroxidase) and the content of peroxide oxidation products (diene conjugates and Malan dialdehyde) in the blood of cattle at the final stage of fattening. The research was conducted during the winter-spring stall on 12-month-old Ukrainian black-spotted dairy cows. According to the principle of analogs, five groups of experimental animals (control and four experimental) were formed, each with six heads. The experiment lasted six months. The rations for the research groups of Bugai cattle are prepared by the recommended norms, taking into account the chemical composition of the fodder of the given area, the age of the animals, live weight, and the planned average daily growth. The silage type of fattening was used for feeding the Bugai cattle. The basis of our dosage of various vitamins of group B for fattening steers of experimental groups is the appropriate percentage of the recommended doses of individual vitamins of group B for fattening pigs (10 % – D1, 20 % – D2, 40 % – D3, 60 % – D4 group). The conducted studies established that the addition of a complex of B vitamins (B1, B2, B5, B6, B10, B12) balanced in terms of nutrients and minerals and fat-soluble vitamins A, D, E to the diet of fattening bulls in appropriate doses causes an increase in activity of critical enzymes of the antioxidant defense system in the blood of fattening bulls (the activity of superoxide dismutase increases the most (by 8.9–28.4 %)) and a decrease in the content of both primary (diene conjugates) and secondary (malanic dialdehyde) products of lipid peroxidation in the blood of fattening bulls, which depends on the dose of B vitamins added to the diet (B1, B2, B5, B6, B10, B12). The most significant change in terms of morphological composition in animals third (B1 – 0.040; B2 – 0.06; B5 – 1.2; B6 – 0.25; B10 – 0.0030; B12 – 0.0006 mg/kg body weight) and fourth (B1 – 0.070; B2 – 0.10; B5 – 2.0; B6 – 0.40; B10 – 0.0050; B12 – 0.0010 mg/kg body weight) research groups, and smallest – in bull Ist (B1 – 0.015; B2 – 0.03; B5 – 0.5; B6 – 0.10; B10 – 0.0012; B12 – 0.0002 mg/kg body weight) and research group, which is associated with dose introduced to the diet of calves during the final fattening phase of B vitamins (B1, B2, B5, B6, B10, B12).https://nvlvet.com.ua/index.php/journal/article/view/4946bull, vitamins b (b1, b2, b5, b6, b10, b12), blood, superoxide dismutase, catalase, glutathione peroxidase, diene conjugates, malanic dialdehyde
spellingShingle P. I. Golovach
B. V. Gutyj
I. A. Kolomiiets
D. D. Ostapiv
R. S. Oseredchuk
O. M. Sloboda
The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
bull, vitamins b (b1, b2, b5, b6, b10, b12), blood, superoxide dismutase, catalase, glutathione peroxidase, diene conjugates, malanic dialdehyde
title The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
title_full The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
title_fullStr The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
title_full_unstemmed The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
title_short The effect of B groups vitamins (B1, B2, B5, B6, B10, B12) on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
title_sort effect of b groups vitamins b1 b2 b5 b6 b10 b12 on the activity of antioxidants protection system enzymes and the content of lipids peroxide oxidation products in the blood of feeding cattle
topic bull, vitamins b (b1, b2, b5, b6, b10, b12), blood, superoxide dismutase, catalase, glutathione peroxidase, diene conjugates, malanic dialdehyde
url https://nvlvet.com.ua/index.php/journal/article/view/4946
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