DNA aptamers targeting glycoprotein D enable specific detection of pseudorabies virus (PRV)

DNA aptamers targeting glycoprotein D enable specific detection of pseudorabies virus (PRV)

Abstract Pseudorabies virus (PRV, SuidAlphaherpesvirus 1) causes substantial economic losses in swine production. Here, we report the development of DNA aptamers targeting the PRV glycoprotein D (gD) through an optimized SELEX protocol. After 15 selection cycles, Apt-gD-2 demonstrated nanomolar affi...

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Bibliographic Details
Main Authors: Zhihao Wang, Yan Qiao, Jiafu Zhao, Xiaotian Chang, Heshui Zhu, Chao Zhang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Animal Diseases
Subjects:
Aptamer
Pseudorabies virus
Glycoprotein D
ELASA
Viral diagnosis
Online Access:https://doi.org/10.1186/s44149-025-00164-z
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