Identifying key genetic variants in Alzheimer’s disease progression using Graph Convolutional Networks (GCN) and biological impact analysis
Abstract Alzheimer’s disease (AD) involves complex genetic interactions that remain challenging to model computationally. We present a novel deep learning framework integrating Single Nucleotide Polymorphism (SNP) data with Graph Convolutional Networks (GCNs) to predict gene-disease relationships in...
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| Main Authors: | Belal A. Hamed, Heba Mamdouh Farghaly, Ahmed Omar, Tarek Abd El-Hafeez |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-07-01
|
| Series: | Journal of Big Data |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40537-025-01228-0 |
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