Application value of nucleic acid MALDI-TOF MS in mycobacterial species identification and drug resistance detection in Mycobacterium tuberculosis

Application value of nucleic acid MALDI-TOF MS in mycobacterial species identification and drug resistance detection in Mycobacterium tuberculosis

ABSTRACT Tuberculosis (TB) and non-tuberculous mycobacteria (NTM) infections pose global health threats, requiring swift and accurate identification for effective treatment. This study aims to assess the ability of nucleic acid matrix-assisted laser desorption ionization time-of-flight mass spectrom...

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Main Authors: Xiaofang Liu, Honghong Niu, Donglin Guo, Huixia Gao, Lihong Wu, Jingyang Liu, Chunfeng Bai, Yuxi Li, Peilong Wang, Zhengfeng Zhou, Yuling Wang, Jianqin Liang, Wenping Gong
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:Microbiology Spectrum
Subjects:
nucleic acid
mass spectrometry
Mycobacterium tuberculosis
non-tuberculous mycobacteria
species identification
drug susceptibility
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01545-24
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