<i>Cannabis sativa</i> L. Extract Alleviates Neuropathic Pain and Modulates CB1 and CB2 Receptor Expression in Rat

<i>Cannabis sativa</i> L. Extract Alleviates Neuropathic Pain and Modulates CB1 and CB2 Receptor Expression in Rat

Introduction: <i>Cannabis sativa</i> L. (CSL) extract has pain-relieving potential due to its cannabinoid content, so the effects of two CSL extracts on alleviating neuropathic pain were investigated in vivo. Methods and groups: Male Wistar rats (n = 130) were divided into groups and rec...

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Main Authors: Joanna Bartkowiak-Wieczorek, Agnieszka Bienert, Kamila Czora-Poczwardowska, Radosław Kujawski, Michał Szulc, Przemysław Mikołajczak, Anna-Maria Wizner, Małgorzata Jamka, Marcin Hołysz, Karolina Wielgus, Ryszard Słomski, Edyta Mądry
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Biomolecules
Subjects:
<i>Cannabis sativa</i>
cannabidiol (CBD)
Δ9-tetrahydrocannabinol (THC)
vincristine
gabapentin
gene expression
Online Access:https://www.mdpi.com/2218-273X/14/9/1065
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