Indapamide microhemodynamic effects in patients with essential arterial hypertension
The aim of this study was to investigate microcirculatory (M) changes and andothelin-1 levels in 3-month indapamide treatment. The study included 22patients with essential arterial hypertension (EAH), Stage I-II, and 12 normotensive controls. Microcirculation was assessed by laser Dopplerflowmetry,...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2005-06-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2440 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The aim of this study was to investigate microcirculatory (M) changes and andothelin-1 levels in 3-month indapamide treatment. The study included 22patients with essential arterial hypertension (EAH), Stage I-II, and 12 normotensive controls. Microcirculation was assessed by laser Dopplerflowmetry, endothelin-1 level - by enzyme immunoassay method. The EAH patients demonstrated M heterogeneity, with high prevalence of pathologic M types. Indapamide was effective and safe in EAH treatment, improving M status. Serum levels of endothelin-1 correlated with Doppler flowmetric indices - Aa/IM, alpha-rhythm amplitude, as well as with blood pressure levels. |
|---|---|
| ISSN: | 1560-4071 2618-7620 |