Cell-scale porosity minimizes foreign body reaction and promotes innervated myofiber formation after volumetric muscle loss
Abstract Volumetric muscle loss (VML) from severe traumatic injuries results in irreversible loss of contractile tissue and permanent functional deficits. These injuries resist endogenous healing and clinical treatment due to excessive inflammation, leading to fibrosis, muscle fiber denervation, and...
Saved in:
| Main Authors: | Areli Rodriguez Ayala, George Christ, Donald Griffin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
|
| Series: | npj Regenerative Medicine |
| Online Access: | https://doi.org/10.1038/s41536-025-00395-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Development of Postural Muscles and Their Innervation
by: J. IJkema-Paassen, et al.
Published: (2005-01-01) -
Combinational regenerative inductive effect of bio-adhesive hybrid hydrogels conjugated with hiPSC-derived myofibers and its derived EVs for volumetric muscle regeneration
by: Jiseong Kim, et al.
Published: (2025-01-01) -
Innervation of Facial Muscles Using an Allogeneic Biomaterial in an Experiment
by: L. A. Musina, et al.
Published: (2023-09-01) -
The m6A modification regulates the composition of myofiber types in chicken skeletal muscle
by: Yanju Shan, et al.
Published: (2025-03-01) -
Commentary: benefits and challenges of cellularized scaffolds for treatment of volumetric muscle loss
by: Indranil Sinha, et al.
Published: (2024-06-01)