Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection
The objective: to assess risk factors for tuberculosis relapse during the COVID-19 pandemic.Results. During the retrospective study, medical documents of patients treated for tuberculosis in 2020-2022 were analyzed. 140 patients above 18 years old with confirmed tuberculosis were included: newly dia...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2023-04-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1723 |
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| author | S. V. Smerdin N. N. Sheshelyakina A. I. Shevchenko M. A. Plekhanova R. I. Ludanny T. I. Vorobieva |
| author_facet | S. V. Smerdin N. N. Sheshelyakina A. I. Shevchenko M. A. Plekhanova R. I. Ludanny T. I. Vorobieva |
| author_sort | S. V. Smerdin |
| collection | DOAJ |
| description | The objective: to assess risk factors for tuberculosis relapse during the COVID-19 pandemic.Results. During the retrospective study, medical documents of patients treated for tuberculosis in 2020-2022 were analyzed. 140 patients above 18 years old with confirmed tuberculosis were included: newly diagnosed tuberculosis – 50 patients, early relapses – 50 patients, and late relapses – 40 patients. At the first stage, significant factors for relapse development were identified (ANOVA): diabetes (F=19402,8; p=0,000000), substances abuse (F=547,6; p=0,000000), alcohol abuse (F=149,7; p=0,000000), MDR MTB (F=107,8; p=0,000000), HIV infection (F=72,4; p=0,000000), imprisonment (F=49,5; p=0,000000), chronic respiratory diseases (F=47,1; p=0,000000), smoking (F=29,0; p=0,000000), and social status (F=28,9; p= 0,000000). At the second stage (cluster analysis), factors implementing the risks of development of early or late relapses were identified.As well as before the COVID-19 pandemic, social, medical and biological risk factors play a significant role in the development of tuberculosis relapses; history of COVID-19 was not one of the risk factors; and stratification of the risk factors made it possible to identify factors that contribute to development of both early and late relapses and to determine preventive measures. |
| format | Article |
| id | doaj-art-89177cfb4fe34b27a6732c040b1ec58a |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2023-04-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-89177cfb4fe34b27a6732c040b1ec58a2025-08-20T02:05:47ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062023-04-011012879310.58838/2075-1230-2023-101-2-87-931718Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infectionS. V. Smerdin0N. N. Sheshelyakina1A. I. Shevchenko2M. A. Plekhanova3R. I. Ludanny4T. I. Vorobieva5Moscow Regional Clinical TB Dispensary; M. F. Vladimirsky Moscow Regional Research Clinical InstituteMoscow Regional Clinical TB DispensaryKuban State Medical University, Russian Ministry of Health; Clinical TB Dispensary, Ministry of Health of Krasnodarsky KrayMoscow Regional Clinical TB Dispensary; M. F. Vladimirsky Moscow Regional Research Clinical InstituteMoscow Regional Clinical TB DispensaryMoscow Regional Clinical TB DispensaryThe objective: to assess risk factors for tuberculosis relapse during the COVID-19 pandemic.Results. During the retrospective study, medical documents of patients treated for tuberculosis in 2020-2022 were analyzed. 140 patients above 18 years old with confirmed tuberculosis were included: newly diagnosed tuberculosis – 50 patients, early relapses – 50 patients, and late relapses – 40 patients. At the first stage, significant factors for relapse development were identified (ANOVA): diabetes (F=19402,8; p=0,000000), substances abuse (F=547,6; p=0,000000), alcohol abuse (F=149,7; p=0,000000), MDR MTB (F=107,8; p=0,000000), HIV infection (F=72,4; p=0,000000), imprisonment (F=49,5; p=0,000000), chronic respiratory diseases (F=47,1; p=0,000000), smoking (F=29,0; p=0,000000), and social status (F=28,9; p= 0,000000). At the second stage (cluster analysis), factors implementing the risks of development of early or late relapses were identified.As well as before the COVID-19 pandemic, social, medical and biological risk factors play a significant role in the development of tuberculosis relapses; history of COVID-19 was not one of the risk factors; and stratification of the risk factors made it possible to identify factors that contribute to development of both early and late relapses and to determine preventive measures.https://www.tibl-journal.com/jour/article/view/1723early tuberculosis relapselate tuberculosis relapserisk factors of tuberculosis relapsepandemic of the novel coronavirus infection |
| spellingShingle | S. V. Smerdin N. N. Sheshelyakina A. I. Shevchenko M. A. Plekhanova R. I. Ludanny T. I. Vorobieva Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection Туберкулез и болезни лёгких early tuberculosis relapse late tuberculosis relapse risk factors of tuberculosis relapse pandemic of the novel coronavirus infection |
| title | Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection |
| title_full | Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection |
| title_fullStr | Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection |
| title_full_unstemmed | Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection |
| title_short | Stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection |
| title_sort | stratification of risks of tuberculosis relapses during the pandemic of the novel coronavirus infection |
| topic | early tuberculosis relapse late tuberculosis relapse risk factors of tuberculosis relapse pandemic of the novel coronavirus infection |
| url | https://www.tibl-journal.com/jour/article/view/1723 |
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