Significant correlations of upregulated MPO expression with cytokine imbalance in ankylosing spondylitis patients and the inhibitory effect mediated by mesenchymal stem cells

Significant correlations of upregulated MPO expression with cytokine imbalance in ankylosing spondylitis patients and the inhibitory effect mediated by mesenchymal stem cells

Abstract Background Little is known regarding both the role of myeloperoxidase (MPO) and the impact of mesenchymal stem cells (MSCs) on inflammatory and immune responses in ankylosing spondylitis (AS). This study is aimed to explore the role of MPO and the regulatory effect of umbilical cord-derived...

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Bibliographic Details
Main Authors: Shubei Liu, Chunjuan Yang, Donghua Xu, Bingjie Gu, Minning Shen
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Musculoskeletal Disorders
Subjects:
Ankylosing spondylitis
Myeloperoxidase
Mesenchymal stem cells
Cytokines
Online Access:https://doi.org/10.1186/s12891-025-08458-6
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