Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate
Objectives. This study aimed to assess the effect of addition of bioactive glass (BG) on the setting time and antibacterial activity of mineral trioxide aggregate (MTA) against Enterococcus faecalis (E. faecalis). Materials and Methods. In this in vitro study, BG was synthesized by the sol-gel techn...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2024/4190647 |
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| author | Amin Salem Milani Faezeh Hadinia Yashar Rezaei Mohammad Hossein Soroush Barhaghi Kamal Attari Ahmad Nouroloyouni |
| author_facet | Amin Salem Milani Faezeh Hadinia Yashar Rezaei Mohammad Hossein Soroush Barhaghi Kamal Attari Ahmad Nouroloyouni |
| author_sort | Amin Salem Milani |
| collection | DOAJ |
| description | Objectives. This study aimed to assess the effect of addition of bioactive glass (BG) on the setting time and antibacterial activity of mineral trioxide aggregate (MTA) against Enterococcus faecalis (E. faecalis). Materials and Methods. In this in vitro study, BG was synthesized by the sol-gel technique and added to MTA powder in certain ratios. Three groups of specimens were fabricated from pure MTA, MTA mixed with 10wt% BG, and MTA mixed with 20wt% BG. The setting time of specimens was measured according to ISO9917-2007. Direct contact test was used to assess the antimicrobial activity of the three groups against E. faecalis. Data were analyzed by repeated measures ANOVA (alpha = 0.05). Results. Addition of BG (in both concentrations) to MTA decreased its setting time and improved its antibacterial activity against E. faecalis (p<0.05). By an increase in concentration of BG (20%), the antimicrobial activity further improved (p<0.05). Conclusion. Addition of BG to MTA in 10wt% and 20wt% concentrations decreased its setting time and improved its antibacterial activity against E. faecalis. |
| format | Article |
| id | doaj-art-890e2b7ba860487cb955ab446b432843 |
| institution | Kabale University |
| issn | 1687-8795 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomaterials |
| spelling | doaj-art-890e2b7ba860487cb955ab446b4328432025-02-03T07:23:37ZengWileyInternational Journal of Biomaterials1687-87952024-01-01202410.1155/2024/4190647Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide AggregateAmin Salem Milani0Faezeh Hadinia1Yashar Rezaei2Mohammad Hossein Soroush Barhaghi3Kamal Attari4Ahmad Nouroloyouni5Endodontic DepartmentEndodontic DepartmentDepartment of Dental BiomaterialsDepartment of Medical Bacteriology & VirologyEndodontic DepartmentDepartment of Orofacial Pain and DysfunctionObjectives. This study aimed to assess the effect of addition of bioactive glass (BG) on the setting time and antibacterial activity of mineral trioxide aggregate (MTA) against Enterococcus faecalis (E. faecalis). Materials and Methods. In this in vitro study, BG was synthesized by the sol-gel technique and added to MTA powder in certain ratios. Three groups of specimens were fabricated from pure MTA, MTA mixed with 10wt% BG, and MTA mixed with 20wt% BG. The setting time of specimens was measured according to ISO9917-2007. Direct contact test was used to assess the antimicrobial activity of the three groups against E. faecalis. Data were analyzed by repeated measures ANOVA (alpha = 0.05). Results. Addition of BG (in both concentrations) to MTA decreased its setting time and improved its antibacterial activity against E. faecalis (p<0.05). By an increase in concentration of BG (20%), the antimicrobial activity further improved (p<0.05). Conclusion. Addition of BG to MTA in 10wt% and 20wt% concentrations decreased its setting time and improved its antibacterial activity against E. faecalis.http://dx.doi.org/10.1155/2024/4190647 |
| spellingShingle | Amin Salem Milani Faezeh Hadinia Yashar Rezaei Mohammad Hossein Soroush Barhaghi Kamal Attari Ahmad Nouroloyouni Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate International Journal of Biomaterials |
| title | Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate |
| title_full | Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate |
| title_fullStr | Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate |
| title_full_unstemmed | Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate |
| title_short | Addition of Bioactive Glass Decreases Setting Time and Improves Antibacterial Properties of Mineral Trioxide Aggregate |
| title_sort | addition of bioactive glass decreases setting time and improves antibacterial properties of mineral trioxide aggregate |
| url | http://dx.doi.org/10.1155/2024/4190647 |
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