A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure

The constant monitoring of the population’s diet and assessment of occupational exposure and environmental impacts are the key to determining health risks and understanding the factors contributing to potential abnormalities in developing lifestyle diseases. Extensive long-term lifestyle monitoring...

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Main Author: Angelika Edyta Charkiewicz
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/47/3/206
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author Angelika Edyta Charkiewicz
author_facet Angelika Edyta Charkiewicz
author_sort Angelika Edyta Charkiewicz
collection DOAJ
description The constant monitoring of the population’s diet and assessment of occupational exposure and environmental impacts are the key to determining health risks and understanding the factors contributing to potential abnormalities in developing lifestyle diseases. Extensive long-term lifestyle monitoring studies can provide data on population health risks, including the most common cardiovascular diseases like hypertension. This paper presents research recommendations for future researchers and doctors to improve the diagnosis of hypertension and targeted, personalised treatment. The research proposal includes a lifestyle study, a diagnostic panel with new biomarkers, and an environmental exposure assessment of men working in the metallurgical industry. New developments and improved interventions are constantly being sought, including new biomarkers with high diagnostic utility for cardiovascular diseases like hypertension. This should enable early diagnosis, and consequently allow for appropriate and, most importantly, personalised therapy, and prevent an increase in CVD deaths. Only the effective diagnosis, treatment, and monitoring of hypertension can reduce the risk of developing diseases associated with hypertension. I propose that several new parameters (NO, cfDNA, MPO, PCSK9, MyBPC3, microRNA, TAS, Pb, and Cd) with prognostic and/or predictive potential should be included in screening to confirm the need for the extensive testing of middle-aged men by healthcare professionals due to the risk of hypertension.
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spelling doaj-art-890913bfb4e54b899498c98c9f96450c2025-08-20T03:43:02ZengMDPI AGCurrent Issues in Molecular Biology1467-30371467-30452025-03-0147320610.3390/cimb47030206A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental ExposureAngelika Edyta Charkiewicz0Department of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Białystok, PolandThe constant monitoring of the population’s diet and assessment of occupational exposure and environmental impacts are the key to determining health risks and understanding the factors contributing to potential abnormalities in developing lifestyle diseases. Extensive long-term lifestyle monitoring studies can provide data on population health risks, including the most common cardiovascular diseases like hypertension. This paper presents research recommendations for future researchers and doctors to improve the diagnosis of hypertension and targeted, personalised treatment. The research proposal includes a lifestyle study, a diagnostic panel with new biomarkers, and an environmental exposure assessment of men working in the metallurgical industry. New developments and improved interventions are constantly being sought, including new biomarkers with high diagnostic utility for cardiovascular diseases like hypertension. This should enable early diagnosis, and consequently allow for appropriate and, most importantly, personalised therapy, and prevent an increase in CVD deaths. Only the effective diagnosis, treatment, and monitoring of hypertension can reduce the risk of developing diseases associated with hypertension. I propose that several new parameters (NO, cfDNA, MPO, PCSK9, MyBPC3, microRNA, TAS, Pb, and Cd) with prognostic and/or predictive potential should be included in screening to confirm the need for the extensive testing of middle-aged men by healthcare professionals due to the risk of hypertension.https://www.mdpi.com/1467-3045/47/3/206lifestylenew biomarkershypertensionearly interventionprevention
spellingShingle Angelika Edyta Charkiewicz
A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure
Current Issues in Molecular Biology
lifestyle
new biomarkers
hypertension
early intervention
prevention
title A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure
title_full A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure
title_fullStr A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure
title_full_unstemmed A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure
title_short A Proposal for Research Involving New Biomarkers of Hypertension, Lifestyle, and Environmental Exposure
title_sort proposal for research involving new biomarkers of hypertension lifestyle and environmental exposure
topic lifestyle
new biomarkers
hypertension
early intervention
prevention
url https://www.mdpi.com/1467-3045/47/3/206
work_keys_str_mv AT angelikaedytacharkiewicz aproposalforresearchinvolvingnewbiomarkersofhypertensionlifestyleandenvironmentalexposure
AT angelikaedytacharkiewicz proposalforresearchinvolvingnewbiomarkersofhypertensionlifestyleandenvironmentalexposure