Dataset of pharmacotherapy in autism spectrum disorderMendeley Data
Pharmacological interventions are widely used in autism spectrum disorder (ASD). We investigated the profile of psychopharmaceutical in a sample of children with ASD of low socioeconomic stratum enrolled and the public school in the city of Embu das Artes, Sao Paulo Brazil. From 149 children with a...
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| Language: | English |
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Elsevier
2025-08-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340925005293 |
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| author | Sebastião Gonçalves de Barros Neto Catherine Oliveira de Araújo Renandro de Carvaho Reis Kelson James da Silva Almeida Decio Brunoni Roberta Monterazzo Cysneiros |
| author_facet | Sebastião Gonçalves de Barros Neto Catherine Oliveira de Araújo Renandro de Carvaho Reis Kelson James da Silva Almeida Decio Brunoni Roberta Monterazzo Cysneiros |
| author_sort | Sebastião Gonçalves de Barros Neto |
| collection | DOAJ |
| description | Pharmacological interventions are widely used in autism spectrum disorder (ASD). We investigated the profile of psychopharmaceutical in a sample of children with ASD of low socioeconomic stratum enrolled and the public school in the city of Embu das Artes, Sao Paulo Brazil. From 149 children with a diagnosis of ASD identified in the municipal education department, informant consents were obtained from 129 children's parents. Data collection was performed through clinical evaluation of the children and face to face application of a questionnaire for parents regarding medication use. The participants socioeconomic stratum was mostly C (72.86 %), followed by B (16,27 %), D (10.07 %), and A (0.7 %) who do not undergo specialized multi-professional educational and behavioral intervention. Among the participants 57.36 % were under psychopharmacological intervention and 33.78 % were under a polypharmacy regimen. Typical antipsychotics were used for 35.4 % followed by atypical antipsychotics (27.43 %), antiseizure (19.47 %), and tricyclic antidepressants (7.08 %). The association of risperidone with valproic acid prevailed in 17.68 % of the sample. ASD levels 2 and 3, epilepsy and age were associated with a higher rate of psychopharmaceutical use. The present dataset can be used to investigate the rational use of medication in the ASD population to monitor potential adverse effects, and to compare with the ASD population across the world. |
| format | Article |
| id | doaj-art-88ed2843df9f441a9f09c5c68eb7b41a |
| institution | DOAJ |
| issn | 2352-3409 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj-art-88ed2843df9f441a9f09c5c68eb7b41a2025-08-20T03:18:38ZengElsevierData in Brief2352-34092025-08-016111180210.1016/j.dib.2025.111802Dataset of pharmacotherapy in autism spectrum disorderMendeley DataSebastião Gonçalves de Barros Neto0Catherine Oliveira de Araújo1Renandro de Carvaho Reis2Kelson James da Silva Almeida3Decio Brunoni4Roberta Monterazzo Cysneiros5Laboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 – prédio 28, 10 andar – São Paulo- SP, CEP 04048061, BrazilLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 – prédio 28, 10 andar – São Paulo- SP, CEP 04048061, BrazilPharmaceutical Science Postgraduate Program. Federal University of Piaui. Teresina – PI, BrazilPharmaceutical Science Postgraduate Program. Federal University of Piaui. Teresina – PI, BrazilLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 – prédio 28, 10 andar – São Paulo- SP, CEP 04048061, BrazilLaboratory of Neurobiology, Mackenzie Presbyterian University. Rua da Consolação, 930 – prédio 28, 10 andar – São Paulo- SP, CEP 04048061, Brazil; Corresponding author.Pharmacological interventions are widely used in autism spectrum disorder (ASD). We investigated the profile of psychopharmaceutical in a sample of children with ASD of low socioeconomic stratum enrolled and the public school in the city of Embu das Artes, Sao Paulo Brazil. From 149 children with a diagnosis of ASD identified in the municipal education department, informant consents were obtained from 129 children's parents. Data collection was performed through clinical evaluation of the children and face to face application of a questionnaire for parents regarding medication use. The participants socioeconomic stratum was mostly C (72.86 %), followed by B (16,27 %), D (10.07 %), and A (0.7 %) who do not undergo specialized multi-professional educational and behavioral intervention. Among the participants 57.36 % were under psychopharmacological intervention and 33.78 % were under a polypharmacy regimen. Typical antipsychotics were used for 35.4 % followed by atypical antipsychotics (27.43 %), antiseizure (19.47 %), and tricyclic antidepressants (7.08 %). The association of risperidone with valproic acid prevailed in 17.68 % of the sample. ASD levels 2 and 3, epilepsy and age were associated with a higher rate of psychopharmaceutical use. The present dataset can be used to investigate the rational use of medication in the ASD population to monitor potential adverse effects, and to compare with the ASD population across the world.http://www.sciencedirect.com/science/article/pii/S2352340925005293Autism spectrum disorderPsychopharmaceuticalMedicationEpilepsyAge |
| spellingShingle | Sebastião Gonçalves de Barros Neto Catherine Oliveira de Araújo Renandro de Carvaho Reis Kelson James da Silva Almeida Decio Brunoni Roberta Monterazzo Cysneiros Dataset of pharmacotherapy in autism spectrum disorderMendeley Data Data in Brief Autism spectrum disorder Psychopharmaceutical Medication Epilepsy Age |
| title | Dataset of pharmacotherapy in autism spectrum disorderMendeley Data |
| title_full | Dataset of pharmacotherapy in autism spectrum disorderMendeley Data |
| title_fullStr | Dataset of pharmacotherapy in autism spectrum disorderMendeley Data |
| title_full_unstemmed | Dataset of pharmacotherapy in autism spectrum disorderMendeley Data |
| title_short | Dataset of pharmacotherapy in autism spectrum disorderMendeley Data |
| title_sort | dataset of pharmacotherapy in autism spectrum disordermendeley data |
| topic | Autism spectrum disorder Psychopharmaceutical Medication Epilepsy Age |
| url | http://www.sciencedirect.com/science/article/pii/S2352340925005293 |
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