Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum

Summary: Climate extreme events like heatwaves (HWs) increasingly threaten marine ecosystems. Using the Manila clam Ruditapes philippinarum as a model organism, this study assessed the effects and costs of thermal priming in a realistic scenario. Results showed increased resilience to lethal HWs in...

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Main Authors: Carmen Federica Tucci, Massimo Milan, Giulia Dalla Rovere, Ilaria Bernardini, Serena Ferraresso, Rafaella Franch, Massimiliano Babbucci, Giovanna Monticelli, Mattia Panin, Tomaso Patarnello, Luca Bargelloni, Luca Peruzza
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225013690
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author Carmen Federica Tucci
Massimo Milan
Giulia Dalla Rovere
Ilaria Bernardini
Serena Ferraresso
Rafaella Franch
Massimiliano Babbucci
Giovanna Monticelli
Mattia Panin
Tomaso Patarnello
Luca Bargelloni
Luca Peruzza
author_facet Carmen Federica Tucci
Massimo Milan
Giulia Dalla Rovere
Ilaria Bernardini
Serena Ferraresso
Rafaella Franch
Massimiliano Babbucci
Giovanna Monticelli
Mattia Panin
Tomaso Patarnello
Luca Bargelloni
Luca Peruzza
author_sort Carmen Federica Tucci
collection DOAJ
description Summary: Climate extreme events like heatwaves (HWs) increasingly threaten marine ecosystems. Using the Manila clam Ruditapes philippinarum as a model organism, this study assessed the effects and costs of thermal priming in a realistic scenario. Results showed increased resilience to lethal HWs in primed clams, with significantly higher survival and better defensive behavior compared to naÏve clams. Priming costs were evidenced by a reduced condition index, but hardened animals showed higher antioxidant capacity, upregulation of heat shock response genes, and shifts in microbial composition favoring beneficial taxa. Gene expression analysis revealed environmental memory via upregulation of respiratory chain complex genes, detectable 38 days after priming—the longest reported in molluscs in a controlled setting. Evidence suggests that thermal priming can be an effective mitigation strategy not just for Manila clams but, potentially, for other farmed shellfish species (e.g., oysters and mussels) and for ecological conservation projects against climate extreme events.
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institution DOAJ
issn 2589-0042
language English
publishDate 2025-08-01
publisher Elsevier
record_format Article
series iScience
spelling doaj-art-88d8915c37d74e3aaee73d903db89ee92025-08-20T03:08:36ZengElsevieriScience2589-00422025-08-0128811310810.1016/j.isci.2025.113108Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarumCarmen Federica Tucci0Massimo Milan1Giulia Dalla Rovere2Ilaria Bernardini3Serena Ferraresso4Rafaella Franch5Massimiliano Babbucci6Giovanna Monticelli7Mattia Panin8Tomaso Patarnello9Luca Bargelloni10Luca Peruzza11Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, Italy; NFBC, National Future Biodiversity Center, Palermo, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, ItalyStazione Idrobiologica Umberto D’Ancona, Department of Biology, University of Padova, Padova, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, Italy; NFBC, National Future Biodiversity Center, Palermo, ItalyDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, Italy; NFBC, National Future Biodiversity Center, Palermo, Italy; Corresponding authorDepartment of Comparative Biomedicine and Food Science, University of Padova, Viale dell’università 16, Legnaro, 35020 Padova, Italy; Corresponding authorSummary: Climate extreme events like heatwaves (HWs) increasingly threaten marine ecosystems. Using the Manila clam Ruditapes philippinarum as a model organism, this study assessed the effects and costs of thermal priming in a realistic scenario. Results showed increased resilience to lethal HWs in primed clams, with significantly higher survival and better defensive behavior compared to naÏve clams. Priming costs were evidenced by a reduced condition index, but hardened animals showed higher antioxidant capacity, upregulation of heat shock response genes, and shifts in microbial composition favoring beneficial taxa. Gene expression analysis revealed environmental memory via upregulation of respiratory chain complex genes, detectable 38 days after priming—the longest reported in molluscs in a controlled setting. Evidence suggests that thermal priming can be an effective mitigation strategy not just for Manila clams but, potentially, for other farmed shellfish species (e.g., oysters and mussels) and for ecological conservation projects against climate extreme events.http://www.sciencedirect.com/science/article/pii/S2589004225013690environmental scienceecologyzoology
spellingShingle Carmen Federica Tucci
Massimo Milan
Giulia Dalla Rovere
Ilaria Bernardini
Serena Ferraresso
Rafaella Franch
Massimiliano Babbucci
Giovanna Monticelli
Mattia Panin
Tomaso Patarnello
Luca Bargelloni
Luca Peruzza
Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
iScience
environmental science
ecology
zoology
title Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
title_full Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
title_fullStr Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
title_full_unstemmed Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
title_short Thermal priming mitigates the effects of lethal marine heatwaves on the Manila clam Ruditapes philippinarum
title_sort thermal priming mitigates the effects of lethal marine heatwaves on the manila clam ruditapes philippinarum
topic environmental science
ecology
zoology
url http://www.sciencedirect.com/science/article/pii/S2589004225013690
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