Analysis of cancer-associated glycosyltransferases reveals novel targets of non-small cell lung cancer pathogenesis

Analysis of cancer-associated glycosyltransferases reveals novel targets of non-small cell lung cancer pathogenesis

BackgroundAberrant glycosylation is associated with cancer progression and patient survival, of which the driving genes could act as biomarkers. Our objective was to characterize the expression of glycosylation-related genes to elucidate the heterogeneity between lung adenocarcinoma (LUAD) and lung...

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Bibliographic Details
Main Authors: Chang Liu, Thomas van Ee, Jurriaan Janssen, Ernesto Rodríguez, Yongsoo Kim, Teodora Radonic, Victor W. van Beusechem, Marieke F. Fransen, Idris Bahce, Yvette van Kooyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
glycosylation
mucins
galectins
α2,6-GalNAc-sialylation
non-small cell lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1601368/full
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