Grading the potential safety risk of medications used in hospital care

Objective: The aim of this study was to stratify medications used in hospital care according to their potential risk. Method: The RAND/UCLA Appropriateness Method was used. Anatomical Therapeutic Chemical subgroups were classified according to their potential risk. A literature search, bulletins,...

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Main Authors: Sonia Chamarro Rubio, Gemma García Menéndez, Gema Nieto Gómez, María Angeles Gálvez Múgica, José Luis Calleja López, Beatriz Montero Errasquín, Eva Delgado Silveira, Sagrario Martín-Aragón Álvarez, Teresa Bermejo Vicedo, Ana María Álvarez Díaz, Covadonga Pérez Menéndez Conde, Noelia Vicente Oliveros
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Farmacia Hospitalaria
Subjects:
Online Access:http://www.aulamedica.es/fh/pdf/10840.pdf
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author Sonia Chamarro Rubio
Gemma García Menéndez
Gema Nieto Gómez
María Angeles Gálvez Múgica
José Luis Calleja López
Beatriz Montero Errasquín
Eva Delgado Silveira
Sagrario Martín-Aragón Álvarez
Teresa Bermejo Vicedo
Ana María Álvarez Díaz
Covadonga Pérez Menéndez Conde
Noelia Vicente Oliveros
author_facet Sonia Chamarro Rubio
Gemma García Menéndez
Gema Nieto Gómez
María Angeles Gálvez Múgica
José Luis Calleja López
Beatriz Montero Errasquín
Eva Delgado Silveira
Sagrario Martín-Aragón Álvarez
Teresa Bermejo Vicedo
Ana María Álvarez Díaz
Covadonga Pérez Menéndez Conde
Noelia Vicente Oliveros
author_sort Sonia Chamarro Rubio
collection DOAJ
description Objective: The aim of this study was to stratify medications used in hospital care according to their potential risk. Method: The RAND/UCLA Appropriateness Method was used. Anatomical Therapeutic Chemical subgroups were classified according to their potential risk. A literature search, bulletins, and alerts issued by patient safety organizations were used to identify the potential safety risk of these subgroups. Nine experts in patient/medication safety were selected to score the subgroups for their appropriateness in the classification. Two evaluation rounds were conducted: the first by email and the second by a panel meeting. Results: A total of 298 Anatomical Therapeutic Chemical subgroups were evaluated. They were classified into three scenarios (low, medium, and high risk). In the first round, 266 subgroups were classified as appropriate to the assigned scenario, 32 were classified as uncertain, and none were classified as inappropriate. In the second round, all subgroups were classified as appropriate. The most frequent subgroups in the low-risk scenario belonged to group A “Alimentary tract and metabolism” (44%); the most frequent in the medium-risk scenario belonged to group J “Antiinfectives for systemic use” (32%); and the most frequent in the high-risk scenario belonged to group L “Antineoplastic and immunomodulating agents” (29%) and group N “Nervous system” (26%). Conclusions: Based on the RAND/UCLA appropriateness method, Anatomical Therapeutic Chemical subgroups used in hospital care were classified according to their potential risk (low, medium, or high). These lists can be incorporated into a risk-scoring tool for future patient/medication safety studies.
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spelling doaj-art-88d16b527ec04787af0b8309135342282025-01-02T16:24:38ZengElsevierFarmacia Hospitalaria1130-63432171-86952018-03-014202536110.7399/fh.10840Grading the potential safety risk of medications used in hospital careSonia Chamarro Rubio0Gemma García Menéndez1Gema Nieto Gómez2María Angeles Gálvez Múgica3José Luis Calleja López4Beatriz Montero Errasquín5Eva Delgado Silveira6Sagrario Martín-Aragón Álvarez7Teresa Bermejo Vicedo8Ana María Álvarez Díaz9Covadonga Pérez Menéndez Conde10Noelia Vicente Oliveros11Servicio de Urgencias, Hospital Universitario Ramón y Cajal, MadridServicio de Traumatología, Hospital Universitario Ramón y Cajal, MadridÁrea Hospitalización, Hospital Universitario Ramón y Cajal, MadridDepartamento de Farmacología, Facultad de Farmacia, Universidad Complutense de Madrid, MadridServicio de Medicina Interna, Hospital Universitario Ramón y Cajal, Madrid. SpainServicio de Geriatría, Hospital Universitario Ramón y Cajal, MadridServicio de Farmacia, Hospital Universitario Ramón y Cajal, MadridDepartamento de Farmacología, Facultad de Farmacia, Universidad Complutense de Madrid, MadridServicio de Farmacia, Hospital Universitario Ramón y Cajal, MadridServicio de Farmacia, Hospital Universitario Ramón y Cajal, MadridServicio de Farmacia, Hospital Universitario Ramón y Cajal, MadridHospital Universitario Ramón y Cajal, MadridObjective: The aim of this study was to stratify medications used in hospital care according to their potential risk. Method: The RAND/UCLA Appropriateness Method was used. Anatomical Therapeutic Chemical subgroups were classified according to their potential risk. A literature search, bulletins, and alerts issued by patient safety organizations were used to identify the potential safety risk of these subgroups. Nine experts in patient/medication safety were selected to score the subgroups for their appropriateness in the classification. Two evaluation rounds were conducted: the first by email and the second by a panel meeting. Results: A total of 298 Anatomical Therapeutic Chemical subgroups were evaluated. They were classified into three scenarios (low, medium, and high risk). In the first round, 266 subgroups were classified as appropriate to the assigned scenario, 32 were classified as uncertain, and none were classified as inappropriate. In the second round, all subgroups were classified as appropriate. The most frequent subgroups in the low-risk scenario belonged to group A “Alimentary tract and metabolism” (44%); the most frequent in the medium-risk scenario belonged to group J “Antiinfectives for systemic use” (32%); and the most frequent in the high-risk scenario belonged to group L “Antineoplastic and immunomodulating agents” (29%) and group N “Nervous system” (26%). Conclusions: Based on the RAND/UCLA appropriateness method, Anatomical Therapeutic Chemical subgroups used in hospital care were classified according to their potential risk (low, medium, or high). These lists can be incorporated into a risk-scoring tool for future patient/medication safety studies.http://www.aulamedica.es/fh/pdf/10840.pdfRisk assessmentRisk managementMedication errorsHospital;RAND/UCLA Appropriateness Method
spellingShingle Sonia Chamarro Rubio
Gemma García Menéndez
Gema Nieto Gómez
María Angeles Gálvez Múgica
José Luis Calleja López
Beatriz Montero Errasquín
Eva Delgado Silveira
Sagrario Martín-Aragón Álvarez
Teresa Bermejo Vicedo
Ana María Álvarez Díaz
Covadonga Pérez Menéndez Conde
Noelia Vicente Oliveros
Grading the potential safety risk of medications used in hospital care
Farmacia Hospitalaria
Risk assessment
Risk management
Medication errors
Hospital;
RAND/UCLA Appropriateness Method
title Grading the potential safety risk of medications used in hospital care
title_full Grading the potential safety risk of medications used in hospital care
title_fullStr Grading the potential safety risk of medications used in hospital care
title_full_unstemmed Grading the potential safety risk of medications used in hospital care
title_short Grading the potential safety risk of medications used in hospital care
title_sort grading the potential safety risk of medications used in hospital care
topic Risk assessment
Risk management
Medication errors
Hospital;
RAND/UCLA Appropriateness Method
url http://www.aulamedica.es/fh/pdf/10840.pdf
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