Comparison of outcomes with and without intrastent placement during PMS surgery

Abstract To assess the efficacy of using a nylon suture as a stent in the PreserFlo MicroShunt (PMS) lumen to prevent postoperative hypotony, 59 eyes that underwent PMS implantation with follow-up for > 6 months were analyzed. Patients were divided into no intrastenting (NST) and intrastenting (S...

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Main Authors: Yusaku Miura, Ken Fukuda, Kenji Yamashiro
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87259-2
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author Yusaku Miura
Ken Fukuda
Kenji Yamashiro
author_facet Yusaku Miura
Ken Fukuda
Kenji Yamashiro
author_sort Yusaku Miura
collection DOAJ
description Abstract To assess the efficacy of using a nylon suture as a stent in the PreserFlo MicroShunt (PMS) lumen to prevent postoperative hypotony, 59 eyes that underwent PMS implantation with follow-up for > 6 months were analyzed. Patients were divided into no intrastenting (NST) and intrastenting (ST) groups, with the ST group subdivided into 9 − 0 nylon suture fully placed (9 F), 9 − 0 nylon suture placement in only half of the lumen (9 H), 10 − 0 nylon suture fully placed (10 F), and 10 − 0 nylon suture placement in only half of the lumen (10 H). The distribution was as follows: 23 eyes in the NST group, 10 in the 9 F group, 9 in the 9 H group, 11 in the 10 F group, and 6 in the 10 H group. No significant differences were observed in preoperative and 6-month postoperative intraocular pressure, number of glaucoma medications, or cumulative survival rate between groups. Postoperative hypotony occurred in 13 eyes (56.5%) in the NST group, one (2.78%) in the ST group (p = 0.00014). Post-intrastent removal, hypotony occurred in 6 eyes (16.7%) in the ST group. These findings suggest that intrastent placement effectively prevents postoperative hypotony, regardless of nylon suture diameter or insertion length; however, timing is crucial as hypotony may occur after removal.
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spelling doaj-art-88d13e4e7df94d6589022e9d6e0d0f652025-01-26T12:31:44ZengNature PortfolioScientific Reports2045-23222025-01-011511710.1038/s41598-025-87259-2Comparison of outcomes with and without intrastent placement during PMS surgeryYusaku Miura0Ken Fukuda1Kenji Yamashiro2Department of Ophthalmology and Visual Science, Kochi Medical School, Kochi UniversityDepartment of Ophthalmology and Visual Science, Kochi Medical School, Kochi UniversityDepartment of Ophthalmology and Visual Science, Kochi Medical School, Kochi UniversityAbstract To assess the efficacy of using a nylon suture as a stent in the PreserFlo MicroShunt (PMS) lumen to prevent postoperative hypotony, 59 eyes that underwent PMS implantation with follow-up for > 6 months were analyzed. Patients were divided into no intrastenting (NST) and intrastenting (ST) groups, with the ST group subdivided into 9 − 0 nylon suture fully placed (9 F), 9 − 0 nylon suture placement in only half of the lumen (9 H), 10 − 0 nylon suture fully placed (10 F), and 10 − 0 nylon suture placement in only half of the lumen (10 H). The distribution was as follows: 23 eyes in the NST group, 10 in the 9 F group, 9 in the 9 H group, 11 in the 10 F group, and 6 in the 10 H group. No significant differences were observed in preoperative and 6-month postoperative intraocular pressure, number of glaucoma medications, or cumulative survival rate between groups. Postoperative hypotony occurred in 13 eyes (56.5%) in the NST group, one (2.78%) in the ST group (p = 0.00014). Post-intrastent removal, hypotony occurred in 6 eyes (16.7%) in the ST group. These findings suggest that intrastent placement effectively prevents postoperative hypotony, regardless of nylon suture diameter or insertion length; however, timing is crucial as hypotony may occur after removal.https://doi.org/10.1038/s41598-025-87259-2GlaucomaPreserFlo microShuntPostoperative hypotony
spellingShingle Yusaku Miura
Ken Fukuda
Kenji Yamashiro
Comparison of outcomes with and without intrastent placement during PMS surgery
Scientific Reports
Glaucoma
PreserFlo microShunt
Postoperative hypotony
title Comparison of outcomes with and without intrastent placement during PMS surgery
title_full Comparison of outcomes with and without intrastent placement during PMS surgery
title_fullStr Comparison of outcomes with and without intrastent placement during PMS surgery
title_full_unstemmed Comparison of outcomes with and without intrastent placement during PMS surgery
title_short Comparison of outcomes with and without intrastent placement during PMS surgery
title_sort comparison of outcomes with and without intrastent placement during pms surgery
topic Glaucoma
PreserFlo microShunt
Postoperative hypotony
url https://doi.org/10.1038/s41598-025-87259-2
work_keys_str_mv AT yusakumiura comparisonofoutcomeswithandwithoutintrastentplacementduringpmssurgery
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