Case Report: Effective methotrexate removal by combined hemodialysis and polymeric resin hemoadsorption
BackgroundHigh-dose methotrexate (HDMTX) is central to treating primary central nervous system lymphoma but carries a risk of acute kidney injury (AKI), which can delay methotrexate (MTX) clearance and increase toxicity. Glucarpidase is the treatment of choice for MTX toxicity, but limited access in...
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| Main Authors: | Maria Rita Dias, Carla Nicolau, Hugo Ferreira, Sérgio Chacim, Isabel Oliveira, Gonçalo de Câmara Negalha, José Mário Mariz, José Maximino Costa |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Nephrology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneph.2025.1644079/full |
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