Tuberculin skin test reversion following isoniazid preventive therapy reflects diversity of immune response to primary Mycobacterium tuberculosis infection.

Tuberculin skin test reversion following isoniazid preventive therapy reflects diversity of immune response to primary Mycobacterium tuberculosis infection.

<h4>Rationale</h4>Healthy household contacts (HHC) of individuals with Tuberculosis (TB) with Tuberculin Skin Test (TST) conversions are considered to harbor latent Mycobacterium tuberculosis (Mtb), and at risk for TB. The immunologic, clinical, and public health implications of TST reve...

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Main Authors: Denise F Johnson, LaShaunda L Malone, Sarah Zalwango, Joy Mukisa Oketcho, Keith A Chervenak, Bonnie Thiel, Harriet Mayanja-Kizza, Catherine M Stein, W Henry Boom, Christina L Lancioni, Tuberculosis Research Unit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0096613
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