Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis
Exogenous feed enzymes (EFE) are incorporated into beef cattle diets to improve nutrient utilization and animal performance. This meta-analysis estimates the effects of EFE inclusion on beef cattle performance, feed intake, nutrient digestibility, and ruminal fermentation parameters, while also iden...
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Elsevier
2025-05-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1751731125000643 |
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| author | I.M. Ferreira H.C. Mantovani M. Vedovatto A.S. Cardoso A.A. Rodrigues B.G.C. Homem M.J.I. de Abreu A.N. Rodrigues L.H. Cursino Batista J.S. de Oliveira F.L. Viquez-Umana A.H.P.M Assumpção G.R. Siqueira F.D. de Resende |
| author_facet | I.M. Ferreira H.C. Mantovani M. Vedovatto A.S. Cardoso A.A. Rodrigues B.G.C. Homem M.J.I. de Abreu A.N. Rodrigues L.H. Cursino Batista J.S. de Oliveira F.L. Viquez-Umana A.H.P.M Assumpção G.R. Siqueira F.D. de Resende |
| author_sort | I.M. Ferreira |
| collection | DOAJ |
| description | Exogenous feed enzymes (EFE) are incorporated into beef cattle diets to improve nutrient utilization and animal performance. This meta-analysis estimates the effects of EFE inclusion on beef cattle performance, feed intake, nutrient digestibility, and ruminal fermentation parameters, while also identifying factors influencing these outcomes. We initially screened 94 articles, and 23 studies met the eligibility criteria, contributing data from up to 83 treatment means. The magnitude of the effect (size effect) was determined using weighted mean differences (WMD) between the EFE-treated and control groups (diets without EFE inclusion). Heterogeneity was assessed through meta-regression and subgroup analysis. Results indicated that EFE inclusion did not affect final BW (P ≥ 0.871), DM intake (P ≥ 0.467), average daily gain (P ≥ 0.145), or feed efficiency (P ≥ 0.417). However, a significant increase in hot carcass weight (P = 0.047; WMD = 2.21 kg) was observed. The inclusion of EFE in the diet did not affect the profile of ruminal short-chain fat acid (P ≥ 0.225) or ruminal ammonia nitrogen concentration (N-NH3; P = 0.143). However, EFE inclusion improved the digestibility of DM (P < 0.01; WMD = 16.9 g/kg), CP (P = 0.003; WMD = 20.2 g/kg), and NDF (P = 0.003; WMD = 20.2), with no effect on organic matter or starch digestibility (P ≥ 0.388). Heterogeneity was low (I2 < 25%) for most performance and nutrient digestibility outcomes, indicating consistent effect size estimates. Moderate heterogeneity (P ≤ 0.057; I2 = 25–50%) was noted for DM and NDF digestibility, with EFE application explaining 28.2% of the variability in DM digestibility (P = 0.032), and fully accounting for the heterogeneity in NDF digestibility (P = 0.045). High heterogeneity was found in ruminal fermentation parameters (P < 0.01; I2 > 50%). Funnel plot analysis revealed no publication bias for most variables (P ≥ 0.10). Overall, this meta-analysis demonstrates that EFE inclusion in beef cattle diets increases hot carcass weight, likely due to enhanced digestibility of DM, CP, and NDF, without affecting rumen fermentation parameters. |
| format | Article |
| id | doaj-art-88b050d2df8d4871934bd4db0c9e64be |
| institution | DOAJ |
| issn | 1751-7311 |
| language | English |
| publishDate | 2025-05-01 |
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| series | Animal |
| spelling | doaj-art-88b050d2df8d4871934bd4db0c9e64be2025-08-20T03:17:57ZengElsevierAnimal1751-73112025-05-0119510148110.1016/j.animal.2025.101481Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysisI.M. Ferreira0H.C. Mantovani1M. Vedovatto2A.S. Cardoso3A.A. Rodrigues4B.G.C. Homem5M.J.I. de Abreu6A.N. Rodrigues7L.H. Cursino Batista8J.S. de Oliveira9F.L. Viquez-Umana10A.H.P.M Assumpção11G.R. Siqueira12F.D. de Resende13Department of Animal Science, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Jaboticabal, São Paulo, Brazil; Agência Paulista de Tecnologia dos Agronegócios (APTA), Colina, São Paulo, Brazil; Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USADepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USA; Corresponding author at: University of Wisconsin-Madison, Madison, WI, USA.Louisiana State University, Dean Lee Research and Extension Center, Alexandria, LA 71302, USADepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USADepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USA; Department of Animal Science, Federal University of Paraíba, Areia, Paraíba, BrazilDepartment of Animal Science, Federal University of Viçosa, Viçosa, Minas Gerais, BrazilDepartment of Animal Science, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Jaboticabal, São Paulo, Brazil; Agência Paulista de Tecnologia dos Agronegócios (APTA), Colina, São Paulo, BrazilDepartment of Animal Science, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Jaboticabal, São Paulo, Brazil; Agência Paulista de Tecnologia dos Agronegócios (APTA), Colina, São Paulo, BrazilDepartment of Animal Science, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Jaboticabal, São Paulo, Brazil; Agência Paulista de Tecnologia dos Agronegócios (APTA), Colina, São Paulo, BrazilDepartment of Animal Science, Federal University of Paraíba, Areia, Paraíba, BrazilDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USADepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI, USADepartment of Animal Science, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Jaboticabal, São Paulo, Brazil; Agência Paulista de Tecnologia dos Agronegócios (APTA), Colina, São Paulo, BrazilDepartment of Animal Science, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP), Jaboticabal, São Paulo, Brazil; Agência Paulista de Tecnologia dos Agronegócios (APTA), Colina, São Paulo, BrazilExogenous feed enzymes (EFE) are incorporated into beef cattle diets to improve nutrient utilization and animal performance. This meta-analysis estimates the effects of EFE inclusion on beef cattle performance, feed intake, nutrient digestibility, and ruminal fermentation parameters, while also identifying factors influencing these outcomes. We initially screened 94 articles, and 23 studies met the eligibility criteria, contributing data from up to 83 treatment means. The magnitude of the effect (size effect) was determined using weighted mean differences (WMD) between the EFE-treated and control groups (diets without EFE inclusion). Heterogeneity was assessed through meta-regression and subgroup analysis. Results indicated that EFE inclusion did not affect final BW (P ≥ 0.871), DM intake (P ≥ 0.467), average daily gain (P ≥ 0.145), or feed efficiency (P ≥ 0.417). However, a significant increase in hot carcass weight (P = 0.047; WMD = 2.21 kg) was observed. The inclusion of EFE in the diet did not affect the profile of ruminal short-chain fat acid (P ≥ 0.225) or ruminal ammonia nitrogen concentration (N-NH3; P = 0.143). However, EFE inclusion improved the digestibility of DM (P < 0.01; WMD = 16.9 g/kg), CP (P = 0.003; WMD = 20.2 g/kg), and NDF (P = 0.003; WMD = 20.2), with no effect on organic matter or starch digestibility (P ≥ 0.388). Heterogeneity was low (I2 < 25%) for most performance and nutrient digestibility outcomes, indicating consistent effect size estimates. Moderate heterogeneity (P ≤ 0.057; I2 = 25–50%) was noted for DM and NDF digestibility, with EFE application explaining 28.2% of the variability in DM digestibility (P = 0.032), and fully accounting for the heterogeneity in NDF digestibility (P = 0.045). High heterogeneity was found in ruminal fermentation parameters (P < 0.01; I2 > 50%). Funnel plot analysis revealed no publication bias for most variables (P ≥ 0.10). Overall, this meta-analysis demonstrates that EFE inclusion in beef cattle diets increases hot carcass weight, likely due to enhanced digestibility of DM, CP, and NDF, without affecting rumen fermentation parameters.http://www.sciencedirect.com/science/article/pii/S1751731125000643DigestibilityExogenous enzymesFeedlotHot carcass weightRumen fermentation |
| spellingShingle | I.M. Ferreira H.C. Mantovani M. Vedovatto A.S. Cardoso A.A. Rodrigues B.G.C. Homem M.J.I. de Abreu A.N. Rodrigues L.H. Cursino Batista J.S. de Oliveira F.L. Viquez-Umana A.H.P.M Assumpção G.R. Siqueira F.D. de Resende Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis Animal Digestibility Exogenous enzymes Feedlot Hot carcass weight Rumen fermentation |
| title | Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis |
| title_full | Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis |
| title_fullStr | Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis |
| title_full_unstemmed | Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis |
| title_short | Impact of dietary exogenous feed enzymes on performance, nutrient digestibility, and ruminal fermentation parameters in beef cattle: a meta-analysis |
| title_sort | impact of dietary exogenous feed enzymes on performance nutrient digestibility and ruminal fermentation parameters in beef cattle a meta analysis |
| topic | Digestibility Exogenous enzymes Feedlot Hot carcass weight Rumen fermentation |
| url | http://www.sciencedirect.com/science/article/pii/S1751731125000643 |
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