Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery
Background/Aim. Surgical extraction of impacted lower third molars is inevitably followed by the postoperative occurrence of trismus, swelling, and pain sensations to some degree. Corticosteroids (dexamethasone in particular) are commonly used drugs in the prevention of these complications. The aim...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2023-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | https://doiserbia.nb.rs/img/doi/0042-8450/2023/0042-84502200062D.pdf |
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| author | Đorđević Filip Bubalo Marija Perić Dejan Mihailović Đorđe Bukumirić Zoran Dubovina Dejan |
| author_facet | Đorđević Filip Bubalo Marija Perić Dejan Mihailović Đorđe Bukumirić Zoran Dubovina Dejan |
| author_sort | Đorđević Filip |
| collection | DOAJ |
| description | Background/Aim. Surgical extraction of impacted lower third molars is inevitably followed by the postoperative occurrence of trismus, swelling, and pain sensations to some degree. Corticosteroids (dexamethasone in particular) are commonly used drugs in the prevention of these complications. The aim of this study was to determine the effectiveness of dexamethasone in the prevention of postoperative complications, edema, trismus, and pain after the surgical extraction of impacted lower third molars, depending on the method of its administration. Methods. This prospective study involved 30 healthy patients, aged 18 years and above, of both sexes, with fully impacted lower third molar – class I or II and position B or C, according to Pell and Gregory classification system and vertical position according to Winter classification. All patients were divided randomly into three groups de-pending on the way of dexamethasone administration: oral – dexamethasone administered in the form of oral tablets in a dose of 4 mg one hour before the surgery; submucosal – dexamethasone solution administered submucosally in a dose of 4 mg in the area of the buccal sulcus, after the inferior alveolar nerve block anesthesia and additional anesthesia for the buccal nerve; intramuscular – dexamethasone solution administered intramuscularly in a dose of 4mg into the area of the deltoid muscle, right before the intervention. Preoperatively and at every follow-up (on the first, second, and seventh day postoperatively), interincisal distance, the degree of edema, and the level of pain with the use of a visual analog scale (VAS) were measured. On the seventh postoperative day, the total number of analgesics taken by the patients was recorded. Results. In the postoperative period, there was no statistically significant difference be-tween the examined groups in terms of effectiveness in swelling, trismus, and pain reduction (p > 0.05). Conclusion. There is no significant difference in dexamethasone effectiveness in postoperative trismus, swelling, and pain reduction after the third lower molar surgery, regarding the route of administration – oral, intramuscular, or local submucosal. |
| format | Article |
| id | doaj-art-88977255c3084fe8a9a28581ce3eb182 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-88977255c3084fe8a9a28581ce3eb1822025-08-20T01:58:37ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202023-01-0180433734210.2298/VSP220331062D0042-84502200062DEffectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgeryĐorđević Filip0https://orcid.org/0000-0003-4986-2296Bubalo Marija1Perić Dejan2Mihailović Đorđe3Bukumirić Zoran4https://orcid.org/0000-0002-7609-4504Dubovina Dejan5University of Priština/Kosovska Mitrovica, Faculty of Medical Sciences, Department of Oral Surgery, Kosovska Mitrovica, SerbiaMilitary Medical Academy, Dentistry Clinic, Belgrade, SerbiaUniversity of Priština/Kosovska Mitrovica, Faculty of Medical Sciences, Department of Oral Surgery, Kosovska Mitrovica, SerbiaUniversity of Priština/Kosovska Mitrovica, Faculty of Medical Sciences, Department of Oral Surgery, Kosovska Mitrovica, SerbiaUniversity of Belgrade, Faculty of Medicine, Belgrade, SerbiaUniversity of Priština/Kosovska Mitrovica, Faculty of Medical Sciences, Department of Oral Surgery, Kosovska Mitrovica, SerbiaBackground/Aim. Surgical extraction of impacted lower third molars is inevitably followed by the postoperative occurrence of trismus, swelling, and pain sensations to some degree. Corticosteroids (dexamethasone in particular) are commonly used drugs in the prevention of these complications. The aim of this study was to determine the effectiveness of dexamethasone in the prevention of postoperative complications, edema, trismus, and pain after the surgical extraction of impacted lower third molars, depending on the method of its administration. Methods. This prospective study involved 30 healthy patients, aged 18 years and above, of both sexes, with fully impacted lower third molar – class I or II and position B or C, according to Pell and Gregory classification system and vertical position according to Winter classification. All patients were divided randomly into three groups de-pending on the way of dexamethasone administration: oral – dexamethasone administered in the form of oral tablets in a dose of 4 mg one hour before the surgery; submucosal – dexamethasone solution administered submucosally in a dose of 4 mg in the area of the buccal sulcus, after the inferior alveolar nerve block anesthesia and additional anesthesia for the buccal nerve; intramuscular – dexamethasone solution administered intramuscularly in a dose of 4mg into the area of the deltoid muscle, right before the intervention. Preoperatively and at every follow-up (on the first, second, and seventh day postoperatively), interincisal distance, the degree of edema, and the level of pain with the use of a visual analog scale (VAS) were measured. On the seventh postoperative day, the total number of analgesics taken by the patients was recorded. Results. In the postoperative period, there was no statistically significant difference be-tween the examined groups in terms of effectiveness in swelling, trismus, and pain reduction (p > 0.05). Conclusion. There is no significant difference in dexamethasone effectiveness in postoperative trismus, swelling, and pain reduction after the third lower molar surgery, regarding the route of administration – oral, intramuscular, or local submucosal.https://doiserbia.nb.rs/img/doi/0042-8450/2023/0042-84502200062D.pdfdexamethasonedrug administration routesmolar, thirdoral surgical procedurestrismus |
| spellingShingle | Đorđević Filip Bubalo Marija Perić Dejan Mihailović Đorđe Bukumirić Zoran Dubovina Dejan Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery Vojnosanitetski Pregled dexamethasone drug administration routes molar, third oral surgical procedures trismus |
| title | Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery |
| title_full | Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery |
| title_fullStr | Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery |
| title_full_unstemmed | Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery |
| title_short | Effectivness of submucosal, oral and intramuscular routs of dexamethasone administration in trismus, swelling, and pain reduction after the third lower molar surgery |
| title_sort | effectivness of submucosal oral and intramuscular routs of dexamethasone administration in trismus swelling and pain reduction after the third lower molar surgery |
| topic | dexamethasone drug administration routes molar, third oral surgical procedures trismus |
| url | https://doiserbia.nb.rs/img/doi/0042-8450/2023/0042-84502200062D.pdf |
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