Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention

Bandavirus dabieense (commonly known as severe fever with thrombocytopenia syndrome virus, SFTSV) infection leads to severe fever with thrombocytopenia syndrome (SFTS), which is an emerging tick-borne natural focus disease discovered in middle-eastern China. SFTS is characterized by fever with throm...

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Main Authors: Chengcheng Peng, Yujia Hao, Yuge Yuan, Wenzhou Ma, Duo Zhang, Jienan Kong, He Zhang, Nan Li, Pengpeng Xiao
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
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Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2520343
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author Chengcheng Peng
Yujia Hao
Yuge Yuan
Wenzhou Ma
Duo Zhang
Jienan Kong
He Zhang
Nan Li
Pengpeng Xiao
author_facet Chengcheng Peng
Yujia Hao
Yuge Yuan
Wenzhou Ma
Duo Zhang
Jienan Kong
He Zhang
Nan Li
Pengpeng Xiao
author_sort Chengcheng Peng
collection DOAJ
description Bandavirus dabieense (commonly known as severe fever with thrombocytopenia syndrome virus, SFTSV) infection leads to severe fever with thrombocytopenia syndrome (SFTS), which is an emerging tick-borne natural focus disease discovered in middle-eastern China. SFTS is characterized by fever with thrombocytopenia, and patients’ main clinical manifestations are leucopenia, elevated serum liver enzymes, and multiple organ failure. Ticks are considered as carriers of SFTSV transmission, and Haemaphysalis longicornalis is considered the main vector tick. SFTSV is disseminated through the migration or movement of tick-carrying migratory birds and other animal hosts. With changes in climate and environment, the habitat of ticks such as haemaphysalis longicornalis are continuously expanding, coupled with the diverse animal host species of the ticks. SFTS is evolving into a serious global public safety issue. In the absence of specific treatments and vaccines still being developed, monitoring and vector control are crucial for curbing the spread of SFTSV. Here, based on the existing literature, we reviewed the epidemiology, infection mechanism, clinical characteristics, diagnosis, prevention and clinical treatment of SFTSV to enhance the understanding of the SFTSV, with the aim of providing a theoretical basis guidance for the government and relevant institutions to prevent and control the further spread of SFTSV.
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publishDate 2025-12-01
publisher Taylor & Francis Group
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series Virulence
spelling doaj-art-889328acd85e4a748e6f22c47af40c3a2025-08-20T02:40:14ZengTaylor & Francis GroupVirulence2150-55942150-56082025-12-0116110.1080/21505594.2025.2520343Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and preventionChengcheng Peng0Yujia Hao1Yuge Yuan2Wenzhou Ma3Duo Zhang4Jienan Kong5He Zhang6Nan Li7Pengpeng Xiao8Wenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaDepartment of Pathology, First Affiliated Hospital of Dalian Medical University, Dalian, ChinaChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, ChinaWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, ChinaBandavirus dabieense (commonly known as severe fever with thrombocytopenia syndrome virus, SFTSV) infection leads to severe fever with thrombocytopenia syndrome (SFTS), which is an emerging tick-borne natural focus disease discovered in middle-eastern China. SFTS is characterized by fever with thrombocytopenia, and patients’ main clinical manifestations are leucopenia, elevated serum liver enzymes, and multiple organ failure. Ticks are considered as carriers of SFTSV transmission, and Haemaphysalis longicornalis is considered the main vector tick. SFTSV is disseminated through the migration or movement of tick-carrying migratory birds and other animal hosts. With changes in climate and environment, the habitat of ticks such as haemaphysalis longicornalis are continuously expanding, coupled with the diverse animal host species of the ticks. SFTS is evolving into a serious global public safety issue. In the absence of specific treatments and vaccines still being developed, monitoring and vector control are crucial for curbing the spread of SFTSV. Here, based on the existing literature, we reviewed the epidemiology, infection mechanism, clinical characteristics, diagnosis, prevention and clinical treatment of SFTSV to enhance the understanding of the SFTSV, with the aim of providing a theoretical basis guidance for the government and relevant institutions to prevent and control the further spread of SFTSV.https://www.tandfonline.com/doi/10.1080/21505594.2025.2520343Bandavirus dabieenseepidemiologydiagnosispreventiontreatment
spellingShingle Chengcheng Peng
Yujia Hao
Yuge Yuan
Wenzhou Ma
Duo Zhang
Jienan Kong
He Zhang
Nan Li
Pengpeng Xiao
Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention
Virulence
Bandavirus dabieense
epidemiology
diagnosis
prevention
treatment
title Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention
title_full Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention
title_fullStr Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention
title_full_unstemmed Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention
title_short Bandavirus dabieense: A review of epidemiology, clinical characteristics, pathophysiology, treatment and prevention
title_sort bandavirus dabieense a review of epidemiology clinical characteristics pathophysiology treatment and prevention
topic Bandavirus dabieense
epidemiology
diagnosis
prevention
treatment
url https://www.tandfonline.com/doi/10.1080/21505594.2025.2520343
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