Metabolism Analysis of Alantolactone and Isoalantolactone in Rats by Oral Administration

Alantolactone and isoalantolactone are the major active ingredients of Inulae Radix. Their metabolism in vivo and in vitro was investigated by UPLC-Q-TOF-MS for the first time. As a result, nine metabolites in vivo including cysteine conjugates, oxidates, dehydrogenates, and hydrates were detected i...

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Bibliographic Details
Main Authors: Mengyue Wang, Renjie Xu, Ying Peng, Xiaobo Li
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2018/2026357
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