Neurologic Deficit Score at 4–5 Days Post-eCPR Predicts Long-Term Brain Dysfunction in Rats Following Cardiac Arrest

Neurologic Deficit Score at 4–5 Days Post-eCPR Predicts Long-Term Brain Dysfunction in Rats Following Cardiac Arrest

Cardiac arrest (CA) survivors often develop long-term neurological deficits, but its long-term impact on vulnerable brain regions and neurological outcomes remains unclear. In a previous CA model with conventional cardiopulmonary resuscitation, we found reduced heme oxygenase (HO) activity in the hi...

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Bibliographic Details
Main Authors: Wolfgang Weihs, Alexandra-Maria Stommel, Andrea Müllebner, Alexander Franz Szinovatz, Matthias Müller, Ingrid Magnet, Michael Holzer, Andrey V. Kozlov, Sandra Högler, J. Catharina Duvigneau
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomolecules
Subjects:
rat model
ventricular fibrillation cardiac arrest
hippocampus
cortex
neurodegeneration
heme oxygenase
Online Access:https://www.mdpi.com/2218-273X/15/5/732
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