A repurposed AMP binding domain reveals mitochondrial protein AMPylation as a regulator of cellular metabolism
Abstract Protein AMPylation, the covalent addition of adenosine monophosphate (AMP) to protein substrates, has been known as a post translational modification for over 50 years. Research in this field is largely underdeveloped due to the lack of tools that enable the systematic identification of AMP...
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| Main Authors: | Abner Gonzalez, Alex Pon, Kelly Servage, Krzysztof Pawłowski, Yan Han, Anju Sreelatha |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-63014-z |
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