A Phase II Trial of Melphalan Based Reduced-Intensity Conditioning for Transplantation of T-Replete HLA-Haploidentical Peripheral Blood Stem Cells with Posttransplant Cyclophosphamide in Patients with Hematologic Malignancies

A Phase II Trial of Melphalan Based Reduced-Intensity Conditioning for Transplantation of T-Replete HLA-Haploidentical Peripheral Blood Stem Cells with Posttransplant Cyclophosphamide in Patients with Hematologic Malignancies

T-replete haploidentical donor transplants using posttransplant cyclophosphamide (haplo) have greatly expanded donor availability and are increasingly utilized. Haplo were originally performed using truly nonmyeloablative conditioning and a bone marrow graft. We have also developed myeloablative con...

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Bibliographic Details
Main Authors: Melhem M. Solh, Gabriel Hinojosa, Justin Laporte, Scott R. Solomon, Lawrence E. Morris, Xu Zhang, H. Kent Holland, Asad Bashey
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2021/8868142
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