MTHFD2-mediated redox homeostasis promotes gastric cancer progression under hypoxic conditions

MTHFD2-mediated redox homeostasis promotes gastric cancer progression under hypoxic conditions

Objectives: Cancer cells undergo metabolic reprogramming to adapt to high oxidative stress, but little is known about how metabolic remodeling enables gastric cancer cells to survive stress associated with aberrant reactive oxygen species (ROS) production. Here, we aimed to identify the key metaboli...

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Bibliographic Details
Main Authors:	Hai-Yu Mo, Ruo-Bing Wang, Meng-Yao Ma, Yi Zhang, Xin-Yu Li, Wang-Rong Wen, Yi Han, Tian Tian
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Series:	Redox Report
Subjects:	Gastric cancer methylene tetrahydrofolate dehydrogenase 2 (MTHFD2) redox metabolism NADPH reactive oxygen species (ROS)
Online Access:	https://www.tandfonline.com/doi/10.1080/13510002.2024.2345455
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