Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives
In this work, a series of novel Mannich's bases incorporated with Ibuprofen core and Biginelli derivatives have been reported. The synthesis process was dependent on linking Ibuprofen hydrazone with Isatin to Biginelli derivatives via methylene group of formaldehyde. The new compounds have bee...
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| Format: | Article |
| Language: | English |
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Tikrit University
2023-01-01
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| Series: | Tikrit Journal of Pure Science |
| Subjects: | |
| Online Access: | https://tjpsj.org/index.php/tjps/article/view/716 |
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| _version_ | 1849426857569550336 |
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| author | Layth W. Abdullah Hanaa K.Saleh Mustafa R. Aeyyd |
| author_facet | Layth W. Abdullah Hanaa K.Saleh Mustafa R. Aeyyd |
| author_sort | Layth W. Abdullah |
| collection | DOAJ |
| description |
In this work, a series of novel Mannich's bases incorporated with Ibuprofen core and Biginelli derivatives have been reported. The synthesis process was dependent on linking Ibuprofen hydrazone with Isatin to Biginelli derivatives via methylene group of formaldehyde. The new compounds have been characterized using FT-IR spectroscopy, 1H-NMR spectroscopy and the physical properties.
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| format | Article |
| id | doaj-art-885b5bbc9c88470e94b12aa59a1b8f6d |
| institution | Kabale University |
| issn | 1813-1662 2415-1726 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Tikrit University |
| record_format | Article |
| series | Tikrit Journal of Pure Science |
| spelling | doaj-art-885b5bbc9c88470e94b12aa59a1b8f6d2025-08-20T03:29:14ZengTikrit UniversityTikrit Journal of Pure Science1813-16622415-17262023-01-0122310.25130/tjps.v22i3.716Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli DerivativesLayth W. AbdullahHanaa K.SalehMustafa R. Aeyyd In this work, a series of novel Mannich's bases incorporated with Ibuprofen core and Biginelli derivatives have been reported. The synthesis process was dependent on linking Ibuprofen hydrazone with Isatin to Biginelli derivatives via methylene group of formaldehyde. The new compounds have been characterized using FT-IR spectroscopy, 1H-NMR spectroscopy and the physical properties. https://tjpsj.org/index.php/tjps/article/view/716IbuprofenBiginelli ReactionMannich's bases |
| spellingShingle | Layth W. Abdullah Hanaa K.Saleh Mustafa R. Aeyyd Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives Tikrit Journal of Pure Science Ibuprofen Biginelli Reaction Mannich's bases |
| title | Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives |
| title_full | Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives |
| title_fullStr | Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives |
| title_full_unstemmed | Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives |
| title_short | Synthesis and characterization of novel Mannich's bases incorporated with Ibuprofen an Biginelli Derivatives |
| title_sort | synthesis and characterization of novel mannich s bases incorporated with ibuprofen an biginelli derivatives |
| topic | Ibuprofen Biginelli Reaction Mannich's bases |
| url | https://tjpsj.org/index.php/tjps/article/view/716 |
| work_keys_str_mv | AT laythwabdullah synthesisandcharacterizationofnovelmannichsbasesincorporatedwithibuprofenanbiginelliderivatives AT hanaaksaleh synthesisandcharacterizationofnovelmannichsbasesincorporatedwithibuprofenanbiginelliderivatives AT mustafaraeyyd synthesisandcharacterizationofnovelmannichsbasesincorporatedwithibuprofenanbiginelliderivatives |