Typhoid conjugate vaccine implementation in India: A review of supportive evidence

Background: Typhoid conjugate vaccines are available in the private market in India and are also recommended by the National Technical Advisory Group on Immunisation (NTAGI) for inclusion in India’s Universal Immunisation Programme in 2022 to control and prevent typhoid fever. Our study aims to synt...

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Main Authors: Vijayalaxmi V. Mogasale, Anish Sinha, Jacob John, Habib Hasan Farooqui, Arindam Ray, Tracey Chantler, Vittal Mogasale, Bhim Gopal Dhoubhadel, W John Edmunds, Andrew Clark, Kaja Abbas
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Vaccine: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590136224001414
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author Vijayalaxmi V. Mogasale
Anish Sinha
Jacob John
Habib Hasan Farooqui
Arindam Ray
Tracey Chantler
Vittal Mogasale
Bhim Gopal Dhoubhadel
W John Edmunds
Andrew Clark
Kaja Abbas
author_facet Vijayalaxmi V. Mogasale
Anish Sinha
Jacob John
Habib Hasan Farooqui
Arindam Ray
Tracey Chantler
Vittal Mogasale
Bhim Gopal Dhoubhadel
W John Edmunds
Andrew Clark
Kaja Abbas
author_sort Vijayalaxmi V. Mogasale
collection DOAJ
description Background: Typhoid conjugate vaccines are available in the private market in India and are also recommended by the National Technical Advisory Group on Immunisation (NTAGI) for inclusion in India’s Universal Immunisation Programme in 2022 to control and prevent typhoid fever. Our study aims to synthesise the supportive evidence for typhoid conjugate vaccine implementation in the routine immunisation programme of India. Methods: We conducted a literature review to identify supportive evidence for typhoid conjugate vaccine implementation in India based on the key criteria of the World Health Organisation’s Evidence-to-Recommendation framework for National Immunisation Technical Advisory Groups. Results: We synthesised evidence on typhoid disease burden, benefits and harms of typhoid conjugate vaccine, cost-effectiveness analysis, and implementation feasibility. However, the in-country evidence on budget impact analysis, vaccine demand and supply forecast, equity analysis, target population values and preferences, immunisation service providers’ acceptability, co-administration safety, and antimicrobial resistance tracking were limited. Conclusion: Based on the literature review, we identified evidence gaps. We recommend identifying research priorities for supporting typhoid conjugate vaccine implementation decision-making in India by combining evidence gaps with the perceived importance of the same evidence criteria and factors among immunisation stakeholders.
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institution OA Journals
issn 2590-1362
language English
publishDate 2024-12-01
publisher Elsevier
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series Vaccine: X
spelling doaj-art-884b82a3419d4ffb98d860d87e043bba2025-08-20T02:18:47ZengElsevierVaccine: X2590-13622024-12-012110056810.1016/j.jvacx.2024.100568Typhoid conjugate vaccine implementation in India: A review of supportive evidenceVijayalaxmi V. Mogasale0Anish Sinha1Jacob John2Habib Hasan Farooqui3Arindam Ray4Tracey Chantler5Vittal Mogasale6Bhim Gopal Dhoubhadel7W John Edmunds8Andrew Clark9Kaja Abbas10Department of Infectious Disease Epidemiology and Dynamics, London School of Hygiene & Tropical Medicine, London, UK; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Corresponding author at: Vijayalaxmi V Mogasale, Department of Infectious Disease Epidemiology and Dynamics, London School of Hygiene & Tropical Medicine, London, UK.Indian Institute of Public Health-Gandhinagar, IndiaDepartment of Community Health, Christian Medical College, Vellore, IndiaCollege of Medicine, Qatar University, Doha, QatarDepartment of Infectious Disease & Vaccine Delivery, Bill and Melinda Gates Foundation, New Delhi, IndiaDepartment of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UKGraduate School of Public Health, Yonsei University, Seoul, Republic of Korea (Current affiliation: Health Financing and Economics Department, World Health Organisation, Geneva, Switzerland)School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Department of Clinical Medicine and Research, Institute of Tropical Medicine, Nagasaki University, Nagasaki, JapanDepartment of Infectious Disease Epidemiology and Dynamics, London School of Hygiene & Tropical Medicine, London, UK; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Department of Infectious Disease Epidemiology and Dynamics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, JapanDepartment of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UKDepartment of Infectious Disease Epidemiology and Dynamics, London School of Hygiene & Tropical Medicine, London, UK; School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Department of Infectious Disease Epidemiology and Dynamics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Public Health Foundation of India, New Delhi, IndiaBackground: Typhoid conjugate vaccines are available in the private market in India and are also recommended by the National Technical Advisory Group on Immunisation (NTAGI) for inclusion in India’s Universal Immunisation Programme in 2022 to control and prevent typhoid fever. Our study aims to synthesise the supportive evidence for typhoid conjugate vaccine implementation in the routine immunisation programme of India. Methods: We conducted a literature review to identify supportive evidence for typhoid conjugate vaccine implementation in India based on the key criteria of the World Health Organisation’s Evidence-to-Recommendation framework for National Immunisation Technical Advisory Groups. Results: We synthesised evidence on typhoid disease burden, benefits and harms of typhoid conjugate vaccine, cost-effectiveness analysis, and implementation feasibility. However, the in-country evidence on budget impact analysis, vaccine demand and supply forecast, equity analysis, target population values and preferences, immunisation service providers’ acceptability, co-administration safety, and antimicrobial resistance tracking were limited. Conclusion: Based on the literature review, we identified evidence gaps. We recommend identifying research priorities for supporting typhoid conjugate vaccine implementation decision-making in India by combining evidence gaps with the perceived importance of the same evidence criteria and factors among immunisation stakeholders.http://www.sciencedirect.com/science/article/pii/S2590136224001414Typhoid feverTyphoid conjugate vaccineEvidence-to-RecommendationIndiaImplementation
spellingShingle Vijayalaxmi V. Mogasale
Anish Sinha
Jacob John
Habib Hasan Farooqui
Arindam Ray
Tracey Chantler
Vittal Mogasale
Bhim Gopal Dhoubhadel
W John Edmunds
Andrew Clark
Kaja Abbas
Typhoid conjugate vaccine implementation in India: A review of supportive evidence
Vaccine: X
Typhoid fever
Typhoid conjugate vaccine
Evidence-to-Recommendation
India
Implementation
title Typhoid conjugate vaccine implementation in India: A review of supportive evidence
title_full Typhoid conjugate vaccine implementation in India: A review of supportive evidence
title_fullStr Typhoid conjugate vaccine implementation in India: A review of supportive evidence
title_full_unstemmed Typhoid conjugate vaccine implementation in India: A review of supportive evidence
title_short Typhoid conjugate vaccine implementation in India: A review of supportive evidence
title_sort typhoid conjugate vaccine implementation in india a review of supportive evidence
topic Typhoid fever
Typhoid conjugate vaccine
Evidence-to-Recommendation
India
Implementation
url http://www.sciencedirect.com/science/article/pii/S2590136224001414
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