Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

IntroductionObservational studies have identified associations between hematological traits and type-2 diabetes mellitus (T2D). However, it is difficult to infer causal effects due to the potential of confounding. Our study utilizes the Mendelian randomization (MR) approach to address the above limi...

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Main Authors: Chisom Soremekun, Daudi Jjingo, David Kateete, Oyekanmi Nash, Dorothea Nitsch, Moffat Nyirenda, Dipender Gill, Eleftheria Zeggini, Harald Grallert, Annette Peters, Tinashe Chikowore, Chiara Batini, Opeyemi Soremekun, Segun Fatumo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
Type-2 diabetes
blood cell traits
mendelian randomization
Africa
Hematological traits
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1436972/full
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