The impact of bacterial purine metabolism on antibiotic efficacy
Abstract Metabolism plays a key role in the three antibiotic evasion strategies used by bacteria: tolerance, persistence and resistance. Modulation of purine metabolism is emerging as a common, and clinically relevant, contributor to tolerant and resistant phenotypes. However, whether high or low pu...
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| Main Authors: | Claire E. Stevens, Ashley T. Deventer, Joanne K. Hobbs |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | npj Antimicrobials and Resistance |
| Online Access: | https://doi.org/10.1038/s44259-025-00139-7 |
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