RAG suppresses group 2 innate lymphoid cells

RAG suppresses group 2 innate lymphoid cells

Antigen specificity is the central trait distinguishing adaptive from innate immune function. Assembly of antigen-specific T cell and B cell receptors occurs through V(D)J recombination mediated by the Recombinase Activating Gene endonucleases RAG1 and RAG2 (collectively called RAG). In the absence...

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Main Authors: Aaron M Ver Heul, Madison Mack, Lydia Zamidar, Masato Tamari, Ting-Lin Yang, Anna M Trier, Do-Hyun Kim, Hannah Janzen-Meza, Steven J Van Dyken, Chyi-Song Hsieh, Jenny M Karo, Joseph C Sun, Brian S Kim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
innate lymphoid cell
RAG
inflammation
allergic
dermatitis
atopic
Online Access:https://elifesciences.org/articles/98287
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