Integrated cytomembrane proteomics identifies EpCAM/MGST1 as therapeutic targets in metastatic laryngeal carcinoma

Integrated cytomembrane proteomics identifies EpCAM/MGST1 as therapeutic targets in metastatic laryngeal carcinoma

BackgroundLymph node metastasis plays a crucial role in cancer recurrence and survival, however, the underlying molecular mechanism and biomarkers in laryngeal carcinoma remain poorly characterized. While cytomembrane proteins represent attractive therapeutic targets due to their accessibility, the...

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Bibliographic Details
Main Authors:	Suling Zhuang, Xiaobo Wu, Xiaohuang Lin, Zhihan Li, Di Gan, Shixin Wang, Xue Lin, Gongbiao Lin, Miao Gao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Genetics
Subjects:	lymph node metastasis LSCC cytomembrane protein EpCAM MGST1 lymph node metastasis MGST1
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1615570/full
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