Axial involvement in psoriatic arthritis

Among the variety of clinical manifestations of psoriatic arthritis (PsA) – including peripheral arthritis, dactylitis, enthesitis, and axial disease – spondylitis is the least studied. There is no generally accepted definition of axial PsA (axPsA), nor is there any common terminology or diagnostic...

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Main Authors: E. E. Gubar, T. V. Korotaeva
Format: Article
Language:Russian
Published: IMA PRESS LLC 2022-12-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/3244
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author E. E. Gubar
T. V. Korotaeva
author_facet E. E. Gubar
T. V. Korotaeva
author_sort E. E. Gubar
collection DOAJ
description Among the variety of clinical manifestations of psoriatic arthritis (PsA) – including peripheral arthritis, dactylitis, enthesitis, and axial disease – spondylitis is the least studied. There is no generally accepted definition of axial PsA (axPsA), nor is there any common terminology or diagnostic criteria for it. In the rheumatology community, there is also no consensus regarding radiological and MRI assessment of axial involvement in PsA patients, while disease activity indexes and the therapeutic tactics are borrowed from those used in treating axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS). However, despite a range of similarities in immunopathogenetic mechanisms of axPsA and axSpA, there are also certain differences that may affect the treatment response in these patients. The aim of this review is the analysis of data on axial disease in PsA. The article discusses the genetic features, clinical presentations, imaging techniques, differential diagnostics and treatment options of axPsA.
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spelling doaj-art-883d486ea73b453ab37dcd73fea875232025-08-20T03:22:12ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922022-12-0160654656010.47360/1995-4484-2022-546-5602857Axial involvement in psoriatic arthritisE. E. Gubar0T. V. Korotaeva1V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyAmong the variety of clinical manifestations of psoriatic arthritis (PsA) – including peripheral arthritis, dactylitis, enthesitis, and axial disease – spondylitis is the least studied. There is no generally accepted definition of axial PsA (axPsA), nor is there any common terminology or diagnostic criteria for it. In the rheumatology community, there is also no consensus regarding radiological and MRI assessment of axial involvement in PsA patients, while disease activity indexes and the therapeutic tactics are borrowed from those used in treating axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS). However, despite a range of similarities in immunopathogenetic mechanisms of axPsA and axSpA, there are also certain differences that may affect the treatment response in these patients. The aim of this review is the analysis of data on axial disease in PsA. The article discusses the genetic features, clinical presentations, imaging techniques, differential diagnostics and treatment options of axPsA.https://rsp.mediar-press.net/rsp/article/view/3244psoriatic arthritisspine involvementinflammatory back painspondyloarthritisvisualization methods
spellingShingle E. E. Gubar
T. V. Korotaeva
Axial involvement in psoriatic arthritis
Научно-практическая ревматология
psoriatic arthritis
spine involvement
inflammatory back pain
spondyloarthritis
visualization methods
title Axial involvement in psoriatic arthritis
title_full Axial involvement in psoriatic arthritis
title_fullStr Axial involvement in psoriatic arthritis
title_full_unstemmed Axial involvement in psoriatic arthritis
title_short Axial involvement in psoriatic arthritis
title_sort axial involvement in psoriatic arthritis
topic psoriatic arthritis
spine involvement
inflammatory back pain
spondyloarthritis
visualization methods
url https://rsp.mediar-press.net/rsp/article/view/3244
work_keys_str_mv AT eegubar axialinvolvementinpsoriaticarthritis
AT tvkorotaeva axialinvolvementinpsoriaticarthritis