Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens

Ascites syndrome (AS) is a metabolic disease that seriously affects the growth and development of broiler chickens. Intestinal microbiota play a significant role in the growth of broiler chickens. Therefore, further research on the relationship between AS and intestinal microbiota will help to bette...

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Main Authors: Aikebaier Reheman, Zhichao Wang, Ruihuan Gao, Jiang He, Juncheng Huang, Changqing Shi, Meng Qi, Xinwei Feng
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Veterinary Sciences
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Online Access:https://www.mdpi.com/2306-7381/12/2/126
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author Aikebaier Reheman
Zhichao Wang
Ruihuan Gao
Jiang He
Juncheng Huang
Changqing Shi
Meng Qi
Xinwei Feng
author_facet Aikebaier Reheman
Zhichao Wang
Ruihuan Gao
Jiang He
Juncheng Huang
Changqing Shi
Meng Qi
Xinwei Feng
author_sort Aikebaier Reheman
collection DOAJ
description Ascites syndrome (AS) is a metabolic disease that seriously affects the growth and development of broiler chickens. Intestinal microbiota play a significant role in the growth of broiler chickens. Therefore, further research on the relationship between AS and intestinal microbiota will help to better understand the impact of AS on broiler growth. In this study, 0.2% sodium chloride was added to the drinking water, which induced AS in broiler chickens, and we detected the influence of AS on the growth performance and cecal microbiota of broiler chickens. The results showed that AS significantly reduced the cecal microbial diversity of broiler chickens and affected the cecal microbial composition at the phylum and genus levels (<i>p</i> = 0.05). Further, LEfSe analysis revealed that AS significantly increased the abundance of <i>Bacteroidetes</i> (<i>p</i> = 0.035) while simultaneously reducing the abundance of <i>Actinobacteria</i> (<i>p</i> = 0.031) in the cecum. Additionally, the differential metabolites associated with polycyclic aromatic hydrocarbon degradation were significantly diminished. The findings suggest that AS may further impact the growth rate of broiler chickens by altering cecal microorganisms.
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issn 2306-7381
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series Veterinary Sciences
spelling doaj-art-8831916da50842a8a7e6f78aa090e92c2025-08-20T02:45:38ZengMDPI AGVeterinary Sciences2306-73812025-02-0112212610.3390/vetsci12020126Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler ChickensAikebaier Reheman0Zhichao Wang1Ruihuan Gao2Jiang He3Juncheng Huang4Changqing Shi5Meng Qi6Xinwei Feng7College of Animal Science and Technology, Tarim University, Alar 843300, ChinaEngineering Laboratory of Tarim Animal Diseases Diagnosis and Control, Xinjiang Production & Construction Corps, Alar 843300, ChinaEngineering Laboratory of Tarim Animal Diseases Diagnosis and Control, Xinjiang Production & Construction Corps, Alar 843300, ChinaEngineering Laboratory of Tarim Animal Diseases Diagnosis and Control, Xinjiang Production & Construction Corps, Alar 843300, ChinaKey Laboratory of Livestock and Forage Resources Utilization around Tarim, Ministry of Agriculture and Rural Affairs, Tarim University, Alar 843300, ChinaKey Laboratory of Livestock and Forage Resources Utilization around Tarim, Ministry of Agriculture and Rural Affairs, Tarim University, Alar 843300, ChinaCollege of Animal Science and Technology, Tarim University, Alar 843300, ChinaCollege of Animal Science and Technology, Tarim University, Alar 843300, ChinaAscites syndrome (AS) is a metabolic disease that seriously affects the growth and development of broiler chickens. Intestinal microbiota play a significant role in the growth of broiler chickens. Therefore, further research on the relationship between AS and intestinal microbiota will help to better understand the impact of AS on broiler growth. In this study, 0.2% sodium chloride was added to the drinking water, which induced AS in broiler chickens, and we detected the influence of AS on the growth performance and cecal microbiota of broiler chickens. The results showed that AS significantly reduced the cecal microbial diversity of broiler chickens and affected the cecal microbial composition at the phylum and genus levels (<i>p</i> = 0.05). Further, LEfSe analysis revealed that AS significantly increased the abundance of <i>Bacteroidetes</i> (<i>p</i> = 0.035) while simultaneously reducing the abundance of <i>Actinobacteria</i> (<i>p</i> = 0.031) in the cecum. Additionally, the differential metabolites associated with polycyclic aromatic hydrocarbon degradation were significantly diminished. The findings suggest that AS may further impact the growth rate of broiler chickens by altering cecal microorganisms.https://www.mdpi.com/2306-7381/12/2/126ascites syndromececal microorganisms16S rDNAbroilers
spellingShingle Aikebaier Reheman
Zhichao Wang
Ruihuan Gao
Jiang He
Juncheng Huang
Changqing Shi
Meng Qi
Xinwei Feng
Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens
Veterinary Sciences
ascites syndrome
cecal microorganisms
16S rDNA
broilers
title Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens
title_full Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens
title_fullStr Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens
title_full_unstemmed Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens
title_short Effect of Ascites Syndrome on Diversity of Cecal Microbiota of Broiler Chickens
title_sort effect of ascites syndrome on diversity of cecal microbiota of broiler chickens
topic ascites syndrome
cecal microorganisms
16S rDNA
broilers
url https://www.mdpi.com/2306-7381/12/2/126
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