MicroRNA-155 targets p65 to regulate PD-L1 expression in the early pregnancy endometrium

MicroRNA-155 targets p65 to regulate PD-L1 expression in the early pregnancy endometrium

Abstract Reproductive disorders in dairy cows represent a significant challenge to the advancement of the dairy industry. Pregnancy success is closely related to the mechanism of immune tolerance, with the PD-1/PD-L1 signaling pathway playing a role in immune regulation, which is associated with imm...

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Bibliographic Details
Main Authors: Jinxin Zhang, Yingfang Guo, Han Zhou, Nuoer Chen, Wen Feng, Xinyu Feng, Wenjing Liu, Ganzhen Deng
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Cows
Early pregnant
Uterine epithelium
PD-L1
miR-155
p65
Online Access:https://doi.org/10.1038/s41598-025-94595-w
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