TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES

Regenerative medicine represents the field of medicine that aims to grow lost or damaged human organs and tissues. The promise of regenerative medicine focuses on the development of therapy that can regenerate and restore tissues and organs in the human body. The regenerative medicine  has the poten...

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Main Author: V. A. Tkachuk
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2021-05-01
Series:Сибирский онкологический журнал
Subjects:
Online Access:https://www.siboncoj.ru/jour/article/view/1748
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author V. A. Tkachuk
author_facet V. A. Tkachuk
author_sort V. A. Tkachuk
collection DOAJ
description Regenerative medicine represents the field of medicine that aims to grow lost or damaged human organs and tissues. The promise of regenerative medicine focuses on the development of therapy that can regenerate and restore tissues and organs in the human body. The regenerative medicine  has the potential of cell renewal in our body, reaching about a kilogram per day, tens of tons in our life. Recent data indicate that a tumor is a tissue that largely repeats the pattern of growth and regeneration of normal tissue. Similar to normal stem cells, tumor stem cells are capable of initiating tumor and its growth. Scientists consider that cancer is a payment for multicellularity [1]. Undoubtedly, this potential must be learned to manage. This is a very difficult problem, since many fundamental mechanisms of cell formation and death have not been fully understood. The development of regenerative medicine as a fundamentally new type of medicine will make it  possible not only to control stem cell renewal, but also to prevent malignant transformation. The identification of proteins, micro-RNAs and other factors that regulate the formation and death of cells will identify potential targets  for both stimulating endogenous regeneration and controlling cancer.
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spelling doaj-art-882b0ed852a242b983d0883febeba19a2025-08-20T03:35:48ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682021-05-0120251210.21294/1814-4861-2021-20-2-5-12838TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCESV. A. Tkachuk0Medical Research and Education Center, Institute for Regenerative Medicine, Lomonosov Moscow State UniversityRegenerative medicine represents the field of medicine that aims to grow lost or damaged human organs and tissues. The promise of regenerative medicine focuses on the development of therapy that can regenerate and restore tissues and organs in the human body. The regenerative medicine  has the potential of cell renewal in our body, reaching about a kilogram per day, tens of tons in our life. Recent data indicate that a tumor is a tissue that largely repeats the pattern of growth and regeneration of normal tissue. Similar to normal stem cells, tumor stem cells are capable of initiating tumor and its growth. Scientists consider that cancer is a payment for multicellularity [1]. Undoubtedly, this potential must be learned to manage. This is a very difficult problem, since many fundamental mechanisms of cell formation and death have not been fully understood. The development of regenerative medicine as a fundamentally new type of medicine will make it  possible not only to control stem cell renewal, but also to prevent malignant transformation. The identification of proteins, micro-RNAs and other factors that regulate the formation and death of cells will identify potential targets  for both stimulating endogenous regeneration and controlling cancer.https://www.siboncoj.ru/jour/article/view/1748regenerative medicineoncogenesisreprogrammingtransdifferentiationstem cells secretome
spellingShingle V. A. Tkachuk
TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
Сибирский онкологический журнал
regenerative medicine
oncogenesis
reprogramming
transdifferentiation
stem cells secretome
title TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
title_full TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
title_fullStr TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
title_full_unstemmed TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
title_short TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
title_sort tissue regeneration and oncogenesis similarities and differences
topic regenerative medicine
oncogenesis
reprogramming
transdifferentiation
stem cells secretome
url https://www.siboncoj.ru/jour/article/view/1748
work_keys_str_mv AT vatkachuk tissueregenerationandoncogenesissimilaritiesanddifferences