Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin
We report a 56-year-old woman with regional liver disorder due to acute hepatitis. Computed tomographic images showed low signal density at a plain phase and prolonged contrast effect at a late phase in the left hepatic lobe, in which an accumulation of 99mTc-phytate increased, whereas that of 99mTc...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2017-10-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.215493 |
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| author | Kohei Kotani Joji Kawabe Shigeaki Higashiyama Susumu Shiomi |
| author_facet | Kohei Kotani Joji Kawabe Shigeaki Higashiyama Susumu Shiomi |
| author_sort | Kohei Kotani |
| collection | DOAJ |
| description | We report a 56-year-old woman with regional liver disorder due to acute hepatitis. Computed tomographic images showed low signal density at a plain phase and prolonged contrast effect at a late phase in the left hepatic lobe, in which an accumulation of 99mTc-phytate increased, whereas that of 99mTc-galactosyl human serum albumin (GSA) decreased. Meanwhile, in the right lobe, an accumulation of 99mTc-GSA showed more increased than that of 99mTc-phytate. Liver biopsy showed massive hepatocyte necrosis and interface hepatitis in the left lobe, and moderate hepatitis in the right lobe. Differences in the accumulation between these scintigrams were helpful for understanding rapid necrosis in the left lobe, resulting in a compensatory enlargement of the right lobe. Clinicians should be aware that some cases of acute hepatitis cause regional liver disorder although most cases show homogeneous inflammation. |
| format | Article |
| id | doaj-art-882701f241664604bee62db28dba1eb7 |
| institution | DOAJ |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2017-10-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-882701f241664604bee62db28dba1eb72025-08-20T02:54:43ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122017-10-01160432032310.4103/1450-1147.215493Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albuminKohei Kotani0Joji Kawabe1Shigeaki Higashiyama2Susumu Shiomi3Department of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanDepartment of Nuclear Medicine, Graduate School of Medicine, Osaka City University, Osaka, JapanWe report a 56-year-old woman with regional liver disorder due to acute hepatitis. Computed tomographic images showed low signal density at a plain phase and prolonged contrast effect at a late phase in the left hepatic lobe, in which an accumulation of 99mTc-phytate increased, whereas that of 99mTc-galactosyl human serum albumin (GSA) decreased. Meanwhile, in the right lobe, an accumulation of 99mTc-GSA showed more increased than that of 99mTc-phytate. Liver biopsy showed massive hepatocyte necrosis and interface hepatitis in the left lobe, and moderate hepatitis in the right lobe. Differences in the accumulation between these scintigrams were helpful for understanding rapid necrosis in the left lobe, resulting in a compensatory enlargement of the right lobe. Clinicians should be aware that some cases of acute hepatitis cause regional liver disorder although most cases show homogeneous inflammation.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.215493 99mtc-galactosyl human serum albumin 99mtc-phytateacute hepatitisregional liver disorder |
| spellingShingle | Kohei Kotani Joji Kawabe Shigeaki Higashiyama Susumu Shiomi Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin World Journal of Nuclear Medicine 99mtc-galactosyl human serum albumin 99mtc-phytate acute hepatitis regional liver disorder |
| title | Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin |
| title_full | Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin |
| title_fullStr | Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin |
| title_full_unstemmed | Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin |
| title_short | Regional liver disorder with differences in the accumulation of 99mTc-phytate and 99mTc-galactosyl human serum albumin |
| title_sort | regional liver disorder with differences in the accumulation of 99mtc phytate and 99mtc galactosyl human serum albumin |
| topic | 99mtc-galactosyl human serum albumin 99mtc-phytate acute hepatitis regional liver disorder |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.215493 |
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